154796-66-4

Upstream product

• 155809-03-3 6-(O-tert-butyldiphenylsilyl)-2,4:3,5-di-O-isopropylidene-D-mannose diethyl dithioacetal 
• 3458-28-4 D-Mannose 
• 530-26-7 D-Mannose 
• 6748-69-2 D-mannose diethyl dithioacetal 

Downstream Products

• 154796-70-0 (3S,4R,5R,6S,7S)-3-O-benzyl-8-(O-tert-butyldiphenylsilyl)-3,4,5,6,7,8-hexahydroxy-4,6:5,7-di-O-isopropylidene-1-(2-thiazolyl)-1-octanone 
• 154796-71-1 methyl 3,4,6,7,8-penta-O-benzyl-2-deoxy-1-(2-thiazolyl)-β-D-glycero-D-galacto-octopyranoside 
• 154796-68-6 (4R,5R,6S,7S)-8-(O-tert-butyldiphenylsilyl)-4,5,6,7,8-pentahydroxy-4,6:5,7-di-O-isopropylidene-1-(2-thiazolyl)-2(E)-octen-1-one 

Relevant academic research and scientific papers

Convergent Total Synthesis of Hikizimycin Enabled by Intermolecular Radical Addition to Aldehyde

Hikizimycin (1), which exhibits powerful anthelmintic activity, has the most densely functionalized structure among nucleoside antibiotics. A central 4-amino-4-deoxyundecose of 1 possesses 10 contiguous stereocenters on a C1-C11 linear chain and is decora

Installation of the pyruvate unit in glycidic aldehydes via a Wittig olefination-Michael addition sequence utilizing a thiazole-armed carbonyl ylid. A new stereoselective route to 3-deoxy-2-ulosonic acids and the total synthesis of DAH, KDN, and 4-epi-KDN

A method for the installation of the (2-thiazolylcarbonyl)methylene group, i.e. a masked pyruvate unit owing to the thiazole to formyl equivalence, in sugar-derived aldehydes has been developed. The strategy involves stereoselective carbon-carbon and carb