15482-10-7Relevant academic research and scientific papers
Visible light driven metal-free intramolecular cyclization: A facile synthesis of 3-position substituted 3,4-dihydroisoquinolin-1(2: H)-one
Zou, Shuai,Geng, Shu,Chen, Lina,Wang, Haitao,Huang, Feng
supporting information, p. 380 - 387 (2019/01/10)
A visible-light metal-free photocatalytic synthesis of 3-position substituted 3,4-dihydroisoquinolin-1(2H)-one derivatives under mild conditions in moderate to good yields is described. EosinY Na, an organic dye, which is of low cost and has good availability, is used as the photocatalyst. A wide range of substrates are tolerated and the gram-scale reaction can also proceed smoothly. Mechanistic studies indicate that a plausible free radical process is proposed.
Cobalt(III)-Catalyzed Directed C-H Allylation
Gensch, Tobias,Vásquez-Céspedes, Suhelen,Yu, Da-Gang,Glorius, Frank
supporting information, p. 3714 - 3717 (2015/08/18)
The cobalt(III)-catalyzed allylation was developed for amide-directed C-H activation of arenes, heteroarenes, and olefins. A variety of allyl sources can be employed to introduce this useful functional group.
Direct allylation of aromatic and α,β-unsaturated carboxamides under ruthenium catalysis
Kim, Mirim,Sharma, Satyasheel,Mishra, Neeraj Kumar,Han, Sangil,Park, Jihye,Kim, Minyoung,Shin, Youngmi,Kwak, Jong Hwan,Han, Sang Hoon,Kim, In Su
, p. 11303 - 11306 (2014/11/07)
The ruthenium-catalyzed oxidative allylation of aromatic and α,β-unsaturated carboxamides with allylic carbonates is described. These transformations proceed readily with complete linear γ-selectivity of substituted allylic carbonates. the Partner Organisations 2014.
Ortho-allylation of 1-arylpyrazoles with allyl phenyl ether via iron-catalyzed C-H bond activation under mild conditions
Asako, Sobi,Norinder, Jakob,Ilies, Laurean,Yoshikai, Naohiko,Nakamura, Eiichi
supporting information, p. 1481 - 1485 (2014/06/09)
An iron salt and a bipyridine-type ligand catalyze the ortho-allylation of 1-arylpyrazoles and congeners with allyl phenyl ether under mild conditions (0 °C). The ligand, an organozinc base, and the nature of the allylating reagent are crucial for the success of this reaction. Under these conditions, a competitive phenylation reaction is largely retarded, and cross-coupling of the organozinc with the allyl electrophile is minimized. The reaction may proceed via iron-catalyzed ortho C-H activation to form a metallic intermediate, which then reacts with the allyl ether in a γ selective fashion.
Combined directed ortho metalation - Grubbs metathesis tactics. Synthesis of benzazepine, benzazocine, and benzannulated 7-, 8-, 9-, and 15-membered ring sulfonamide heterocycles
Lane,Snieckus
, p. 1294 - 1296 (2007/10/03)
The rapid construction of diverse benzannulated heterocyclic systems 7, 8, 12a-c, 15a-b, and 21 using Directed ortho Metalation - Ring Closure Metathesis sequences is reported.
