154875-87-3Relevant academic research and scientific papers
Grignard cyclization reaction of fluorinated N-arylimidoyl chlorides: A novel and facile access to 2-fluoroalkyl indoles
Ge, Fenglian,Wang, Zengxue,Wan, Wen,Hao, Jian
, p. 447 - 450 (2008/01/06)
2-Fluoroalkyl-substituted indole derivatives were simply prepared via the Grignard cyclization reaction (GCR) of corresponding fluorinated N-aryl imidoyl chlorides in good yields. This approach provides a novel and facile access to the biologically import
Fluorinated N-[2-(haloalkyl)phenyl]imidoyl chloride, a key intermediate for the synthesis of 2-fluoroalkyl substituted indole derivatives via Grignard cyclization process
Wang, Zengxue,Ge, Fenglian,Wan, Wen,Jiang, Haizhen,Hao, Jian
, p. 1143 - 1152 (2008/02/08)
Fluorinated N-[2-(haloalkyl)phenyl]imidoyl chloride, which was readily available from the corresponding anilines by using Uneyama's one-pot synthesis of fluorinated imidoyl chloride, was found to be a key intermediate for the facile synthesis of 2-fluoroa
