154989-52-3Relevant academic research and scientific papers
Samarium(II) Iodide-promoted Hydroxyalkylations of Indole-3-carbonyls. An Expedient Approach to Pyrrolidinoindoles and Furoindoles
Shiue, Jiann-Shyng,Fang, Jim-Min
, p. 1277 - 1278 (1993)
3-Formyl-, 3-acetyl-1-methylindole and their 2-cyano analogues undergo intra- and inter-molecular hydroxyalkylations on treatment with samarium(II) iodide in the presence of a cosolvent hexamethylphosphoramide; the intramolecular coupling products have th
Indolecarbonyl Coupling Reactions Promoted by Samarium Diiodide. Application to the Synthesis of Indole-Fused Compounds
Lin, Shu-Chen,Yang, Fwu-Duo,Shiue, Jiann-Shyng,Yang, Shyh-Ming,Fang, Jim-Min
, p. 2909 - 2917 (2007/10/03)
By the assistance of an N-sulfonyl group or a cyano group at the C-2 position, hydroxyalkylations of indole-3-carbonyls were achieved by the promotion of samarium diiodide. The indolecarbonyl coupling reactions proceeded in high stereoselectivity via chel
