155193-86-5

Upstream product

• 132565-90-3 4-O-benzoyl-2,3:5,6-di-O-isopropylidene-D-mannose 
• 141410-34-6 5-O-Benzyl-1,2-dideoxy-3,4:6,7-di-O-isopropylidene-D-manno-hept-1-enitol 
• 1426261-16-6 5-benzyloxy-2-deoxy-3,4:6,7-di-O-isopropylidene-D-erythro-D-manno-1-heptanol 
• 1426261-17-7 6-benzyloxy-1,2,3-trideoxy-4,5:7,8-di-O-isopropylidene-D-erythro-D-manno-1-yno-octitol 
• 67-56-1 methanol 
• 1426261-18-8 6-benzyloxy-1-bromo-1,2,3-trideoxy-4,5:7,8-di-O-isopropylidene-D-erythro-D-manno-1-yno-octitol 
• 7757-38-2 2,3,5,6-di-O-isopropylidene-D-mannofuranose 
• 137945-76-7 (R)-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl][(4S,5R)-5-ethenyl-2,2-dimethyl-1,3-dioxolan-4-yl]methanol 
• 100-39-0 benzyl bromide 

Relevant academic research and scientific papers

Formal synthesis of 3-deoxy-d-manno-octulosonic acid (KDO) and 3-deoxy-d-arabino-2-heptulosonic acid (DAH)

Practical synthetic routes to 3-deoxy-d-manno-octulosonic acid (KDO) and 3-deoxy-d-arabino-2-heptulosonic acid (DAH) from common sugar substrates are reported. Chain homologation of the sugar substrates was accomplished by Wittig olefination and Corey-Fuchs alkynylation. A new cyclization strategy was investigated to access the desired pyranosyl isomer of the KDO target. Georg Thieme Verlag Stuttgart New York.

Convenient Synthesis of 3-Deoxy-D-manno-2-octulosonic Acid (KDO) and 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid (KDN) Derivatives from D-Mannose

Horner-Wittig reactions of 4-O-benzyl-2,3:5,6-di-O-isopropylidene-D-mannose and 2,3,4,5,6,7-hexa-O-benzyl-6-D-glycero-2,3,4,5-D-galacto-heptose with methyl 2-benzyloxycarbonylamino-2-(diethoxyphosphoryl)acetate gave the corresponding α-dehydroamino acid d