1552-56-3

Basic information

• Product Name: Benzoxazole, 2-[4-(2-phenylethenyl)phenyl]-
• CAS NO: 1552-56-3
• Molecular Formula: C21H15NO
• Molecular Weight: 297.356
• Mol File: 1552-56-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzoxazole, 2-[4-(2-phenylethenyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoxazole, 2-[4-(2-phenylethenyl)phenyl]-(1552-56-3)
• EPA Substance Registry System: Benzoxazole, 2-[4-(2-phenylethenyl)phenyl]-(1552-56-3)

Safety Data

• Hazardous Substances Data: 1552-56-3(Hazardous Substances Data)

Upstream product

• 117649-27-1 2-(4-bromo-benzylidenamino)-phenol 
• 100-42-5 styrene 
• 3164-13-4 2-(4-bromophenyl)-1,3-benzoxazole 
• 95-55-6 2-amino-phenol 
• 99-94-5 p-Toluic acid 
• 835-71-2 2-(4-methylphenyl)-1,3-benzoxazole 
• 538-51-2 benzylidene phenylamine 

Relevant articles and documents

Facile access to libraries of diversely substituted 2-aryl-benzoxazoles/benzothiazoles from readily accessible aldimines via cyclization/cross coupling in imidazolium-ILs with Pd(OAc)2 or NiCl2 (dppp) as catalyst

A two-step protocol involving Pd-catalyzed cyclization of readily accessible p-bromophenyl-aldimines to 2-bromophenyl-benzoxazole/benzothiazole in [BMIM][PF6] or [BMIM][BF4] as solvent, followed by the Suzuki, Heck, and Sonogashira cross-coupling reactions catalyzed by Pd or Ni is described that generates libraries of diversely substituted 2-aryl-/heteroaryl-benzoxazoles/benzothiazoles in respectable isolated yields under mild reaction conditions. The feasibility to perform the two-steps in sequence in one-pot starting from the aldimines is also demonstrated and the potential for recycling/reuse of the IL solvent is also shown.