155204-23-2Relevant articles and documents
Copper-Mediated Radiofluorination of Arylstannanes with [18F]KF
Makaravage, Katarina J.,Brooks, Allen F.,Mossine, Andrew V.,Sanford, Melanie S.,Scott, Peter J. H.
, p. 5440 - 5443 (2016/11/04)
A copper-mediated nucleophilic radiofluorination of aryl- and vinylstannanes with [18F]KF is described. This method is fast, uses commercially available reagents, and is compatible with both electron-rich and electron-deficient arene substrates. This method has been applied to the manual synthesis of a variety of clinically relevant radiotracers including protected [18F]F-phenylalanine and [18F]F-DOPA. In addition, an automated synthesis of [18F]MPPF is demonstrated that delivers a clinically validated dose of 200 ± 20 mCi with a high specific activity of 2400 ± 900 Ci/mmol.
Synthesis and evaluation of 4-(2'-methoxyphenyl)-1-[2'-[N-(2''- pyridinyl)-p-iodobenzamido]ethyl]piperazine (p-MPPI): A new iodinated 5- HT(1A) ligand [2]
Zhuang,Kung,Kung
, p. 1406 - 1407 (2007/10/02)
-