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15521-65-0

Nickel bis(dimethyldithiocarbamate) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 15521-65-0 Structure

  • Basic information

    1. Product Name: Nickel bis(dimethyldithiocarbamate)
    2. Synonyms: Bis(dimethyldithiocarbamic acid)nickel(II) salt;Ai3-50831;Bis(dimethylcarbamodithioato-S,S')nickel;Einecs 239-560-8;N,N-Dimethyldithiocarbamate nickel salt;METHYL NICLATE;bis(dimethyldithiocarbamato) nickel complex;Nickel bis(dimethyldithiocarbamate)
    3. CAS NO:15521-65-0
    4. Molecular Formula: C6H12N2NiS4
    5. Molecular Weight: 299.13
    6. EINECS: 239-560-8
    7. Product Categories: Organometallics
    8. Mol File: 15521-65-0.mol

  • Chemical Properties

    1. Melting Point: >290°C
    2. Boiling Point: 488.62°C (estimate)
    3. Flash Point: 32 °C
    4. Appearance: COA
    5. Density: 1,77 g/cm3
    6. Vapor Pressure: 10.2mmHg at 25°C
    7. Refractive Index: N/A
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: Nickel bis(dimethyldithiocarbamate)(CAS DataBase Reference)
    11. NIST Chemistry Reference: Nickel bis(dimethyldithiocarbamate)(15521-65-0)
    12. EPA Substance Registry System: Nickel bis(dimethyldithiocarbamate)(15521-65-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: 20/21/22
    3. Safety Statements: 22-36/37/39
    4. WGK Germany:
    5. RTECS:
    6. TSCA: No
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 15521-65-0(Hazardous Substances Data)

15521-65-0 Usage

Safety Profile

Confirmed human carcinogen.Mildly toxic by ingestion.

Check Digit Verification of cas no

The CAS Registry Mumber 15521-65-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,5,2 and 1 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15521-65:
(7*1)+(6*5)+(5*5)+(4*2)+(3*1)+(2*6)+(1*5)=90
90 % 10 = 0
So 15521-65-0 is a valid CAS Registry Number.
InChI:InChI=1/2C3H7NS2.Ni/c2*1-4(2)3(5)6;/h2*1-2H3,(H,5,6);/q;;+2/p-2

15521-65-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-dimethylcarbamodithioate,nickel(2+)

1.2 Other means of identification

Product number -
Other names Dimethyldithiocarbamatonickel

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15521-65-0 SDS

15521-65-0Downstream Products

15521-65-0Relevant articles and documents

Induction of Necroptosis in Cancer Stem Cells using a Nickel(II)-Dithiocarbamate Phenanthroline Complex

Flamme, Marie,Cressey, Paul B.,Lu, Chunxin,Bruno, Peter M.,Eskandari, Arvin,Hemann, Michael T.,Hogarth, Graeme,Suntharalingam, Kogularamanan

, p. 9674 - 9682 (2017/07/22)

The cytotoxic properties of a series of nickel(II)-dithiocarbamate phenanthroline complexes is reported. The complexes 1–6 kill bulk cancer cells and cancer stem cells (CSCs) with micromolar potency. Two of the complexes, 2 and 6, kill twice as many breast cancer stem cell (CSC)-enriched HMLER-shEcad cells as compared to breast CSC-depleted HMLER cells. Complex 2 inhibits mammosphere formation to a similar extent as salinomycin (a CSC-specific toxin). Detailed mechanistic studies suggest that 2 induces CSC death by necroptosis, a programmed form of necrosis. Specifically, 2 triggers MLKL phosphorylation, oligomerization, and translocation to the cell membrane. Additionally, 2 induces necrosome-mediated propidium iodide (PI) uptake and mitochondrial membrane depolarisation, as well as morphological changes consistent with necroptotosis. Strikingly, 2 does not evoke necroptosis by intracellular reactive oxygen species (ROS) production or poly(ADP) ribose polymerase (PARP-1) activation.

THE DIRECT ELECTROCHEMICAL SYNTHESIS OF DIALKYLDITHIOCARBAMATE AND DIETHYLDITHIOPHOSPHATE COMPLEXES OF MAIN GROUP AND TRANSITION METALS

Geloso, Corrado,Kumar, Rajesh,Lopez-Grado, Jaime Romero,Tuck, Dennis G.

, p. 928 - 932 (2007/10/02)

Dialkyldithiocarbamate derivatives (R2NCS2)nM of a number of metals (M=Fe, Co, Ni, Cu, Ag, Zn, Cd, In, Tl) have been synthesised in good yield by electrochemical oxidation of appropriate sacrificial anodes in non-aqueous solutions of either the corresponding tetraalkylthiuran disulphide (R2NCS2)2 (R=Me, Et) or a mixture of carbon disulphide plus the secondary amine R2NH (R=Et, i-Pr; R2NH=piperidine).Similar experiments with solutions of (EtO)2P(S)SH (=HL) gave MLn* derivatives (M=Fe, Co, Ni, Cu, Ag, Au, Zn, Cd, Hg, Ga, In, Tl) while in the presence of HL+1,10-phenanthroline, MLn.phen derivatives were obtained for M=V, Mn, Fe, Co, Zn, and Ga.

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