155235-91-9Relevant academic research and scientific papers
A facile, one-pot synthesis, characterization and antimicrobial activity of o-hydroxy anilide derivatives and 1-substituted-1,3-dicyclohexylurea analogs of long chain carboxylic acids
Farshori, Nida N.,Ahmad, Anis,Khan, Asad U.,Rauf, Abdul
experimental part, p. 1433 - 1438 (2011/04/25)
A series of novel o-hydroxy anilide derivatives and 1-substituted-1,3- dicyclohexylurea analogs of long chain carboxylic acids have been synthesized. The structures of the synthesized compounds were elucidated by IR, 1H NMR, 13C NMR
Chemoselective alcoholysis of acylureas
Kishikawa,Eida,Kohmoto,Yamamoto,Yamada
, p. 173 - 175 (2007/10/02)
Two methods for the chemoselective alcoholysis of acylureas were developed to generate esters and amides, respectively. In alcoholysis using sodium methoxide in methanol, methoxide attacked the acyl carbonyl to give the corresponding methyl ester. While in alcoholysis using lithium benzyloxide in diethyl ether, benzyloxide attacked the urea carbonyl to give the amide. The chemoselectivity originates in the different chelating abilities of the metals and the polarity of the solvents.
