155268-27-2

Upstream product

• 52421-93-9 (2Z)-3-methyl-2-penten-4-ynal 
• 3230-69-1 3-methyl-1-penten-4-yn-3-ol 
• 6153-05-5 (Z)-3-methylpent-2-en-4-ynol 
• 591-50-4 iodobenzene 

Downstream Products

• 1261167-94-5 4,5-dimethyl-1-phenyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid dimethyl ester 
• 1261167-95-6 4,5-dimethyl-1-phenyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylic acid diethyl ester 
• 1001653-76-4 2-(2,6-dimethyl-2-vinyl-hept-5-enyl)-3-methyl-5-phenyl-furan 
• 1001653-39-9 [(Z)-1-((E)-3,7-dimethyl-octa-2,6-dienyloxy)-3-methyl-pent-2-en-4-ynyl]benzene 
• 260543-70-2 (Z)-3-methyl-1-phenylpent-2-en-4-yne-1-thiol 
• 40808-42-2 2,3-dimethyl-5-phenylthiophene 
• 260543-62-2 thioacetic acid (Z)-S-(3-methyl-1-phenylpent-2-en-4-ynyl) ester 
• 73186-37-5 2,3-dimethyl-5-phenylfuran 

Relevant academic research and scientific papers

Synthesis of Furans by Cyclization of 2-En-4-yn-1-ols in the Presence of Ruthenium and Palladium Catalysts

Substituted furans have been synthesized in the presence of ruthenium catalysts under neutral and mild conditions via cyclization of primary and secondary enynols of type (Z)-HCC-C(Me)=CH-CH(R)OH containing a terminal triple bond.The intramolecular addition of the hydroxy group to the triple bond of internal (Z)-enynols is also possible upon palladium catalysis.

Gold(l)-catalyzed formation of furans by a Claisen type rearrangement of ynenyl allyl ethers

A series of ynenyl allyl ethers were rearranged into polysubstituted furans in the presence of a gold(I) catalyst. It is proposed that the transformation involves a Claisen-type rearrangement that allows the efficient creation of quaternary centers under mild experimental conditions.

Synthesis of functionalized furans via gold(I)-catalyzed Claisen-type rearrangement

(Chemical Equation Presented) Gold(I)-catalyzed cyclization of pentenynyl allyl ethers allows the rapid construction of functionalized furans. The concerted oxy-Claisen-type mechanism induces a complete selectivity of the process and allows the easy forma

A general and facile synthesis of substituted furans by palladium- catalyzed cycloisomerization of (Z)-2-en-4-yn-1-ols

A general and facile synthesis of furans, based on Pd(II)-catalyzed cycloisomerization of (Z)-2-en-4-yn-1-ols, is described. Cycloisomerization reactions are carried out at 25-100 °C in the presence of a very simple catalytic system, consisting of K2PdI4, under essentially neutral conditions. This new methodology is very versatile and can be applied to the synthesis of a variety of substituted furans, including particularly fragile, naturally occurring furans such as rosefuran. Efficient synthetic approaches for the regioselective synthesis of suitably substituted (Z)-2-en-4-yn-1-ols have been developed.