155295-75-3

Upstream product

• 122-78-1 phenylacetaldehyde 
• 155295-74-2 3-[2(R)-(cyclopropylmethyl)-1,3-dioxobutyl]-4(S)-(phenylmethyl)-2-oxazolidinone 
• 104266-88-8 (4S)-4-benzyl-3-pent-4-enoyl-1,3-oxazolidin-2-one 
• 155295-65-1 3-(3-cyclopropyl-1-oxopropyl)-4(S)-phenylmethyl-2-oxazolidinone 

Downstream Products

• 220588-98-7 N-[1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl]-2(R)-(cyclopropylmethyl)-3(R),5(R)-dihydroxy-3,5-O-isopropylidene-6-phenylhexanamide 
• 220588-96-5 N-[1(S)-(cyclohexylmethyl)-2(R),3(S)-dihydroxy-5-methylhexyl]-2(R)-(cyclopropylmethyl)-3(S),5(R)-dihydroxy-3,5-O-isopropylidene-6-phenylhexanamide 
• 155417-46-2 3-[2(R)-(cyclopropylmethyl)-3(R),5(R)-dihydroxy-3,5-O-isopropylidene-6-phenyl-1-oxohexyl]-4(S)-(phenylmethyl)-2-oxazolidinone 
• 155417-45-1 3-[2(R)-(cyclopropylmethyl)-3(S),5(R)-dihydroxy-3,5-O-isopropylidene-6-phenyl-1-oxohexyl]-4(S)-(phenylmethyl)-2-oxazolidinone 
• 220588-97-6 (R)-2-((4R,6R)-6-Benzyl-2,2-dimethyl-[1,3]dioxan-4-yl)-3-cyclopropyl-propionic acid 
• 220588-95-4 (R)-2-((4S,6R)-6-Benzyl-2,2-dimethyl-[1,3]dioxan-4-yl)-3-cyclopropyl-propionic acid 

Relevant academic research and scientific papers

Novel small renin inhibitors containing 4,5- or 3,5-Dihydroxy-2-substituted-6-phenylhexanamide replacements at the P2-P3 sites

Renin inhibitors containing a 4,5- or a 3,5-dihydroxy-2-substituted-6-phenylhexanamide fragment at the P2-P3 sites have been prepared and evaluated. The four possible diastereomeric diols of the two series of inhibitors were synthesi