155300-01-9Relevant academic research and scientific papers
Synthesis of the acyltetronic acid ionophore tetronasin (ICI M139603)
Ley, Steven V.,Brown, Dearg S.,Clase, J. Andrew,Fairbanks, Antony J.,Lennon, Ian C.,Osborn, Helen M. I.,Stokes, Elaine S. E.,Wadsworth, David J.
, p. 2259 - 2276 (2007/10/03)
A synthetic strategy for the preparation of tetronasin 1, an acyltetronic acid ionophore demonstrating antibiotic, antiparasitic and growth promotion in ruminants is described. The key step involves a metal mediated cyclization reaction which creates two
Two New Routes to the C19-C26 Tetrahydrofuran Fragment of the Acyl Tetronic Acid Ionophore Tetronasin (ICI M139603)
Boons, Geert-Jan,Brown, Dearg S.,Clase, J. Andrew,Lennon, Ian C.,Ley, Steven V.
, p. 319 - 322 (2007/10/02)
Two highly efficient and complementary synthetic routes to the C19-C26 tetrahydrofuran fragment (2) of the novel acyltetronic acid ionophore antibiotic tetronasin (ICI 139603) (1) are described to provide multigramme quantities of the required product.
