104265-23-8Relevant academic research and scientific papers
Synthesis of the acyltetronic acid ionophore tetronasin (ICI M139603)
Ley, Steven V.,Brown, Dearg S.,Clase, J. Andrew,Fairbanks, Antony J.,Lennon, Ian C.,Osborn, Helen M. I.,Stokes, Elaine S. E.,Wadsworth, David J.
, p. 2259 - 2276 (2007/10/03)
A synthetic strategy for the preparation of tetronasin 1, an acyltetronic acid ionophore demonstrating antibiotic, antiparasitic and growth promotion in ruminants is described. The key step involves a metal mediated cyclization reaction which creates two
Pheromone Synthesis, CXXXV. Synthesis of (4R,5R,6S,7E,9E)-4,6,8-Trimethyl-7,9-undecadien-5-ol and Its Antipode, the Female Specific Compound of the Woodroach Cryptocercus punctulatus
Mori, Kenji,Itou, Masamichi
, p. 87 - 94 (2007/10/02)
(4R,5R,6S,7E,9E)-4,6,8-Trimethyl-7,9-undecadien-5-ol (1) and its antipode 1', the female specific compound of the woodroach Cryptocercus punctulatus, were synthesized by starting from methyl (R)-3-hydroxy-2-methylpropanoate (C). Key Words: Chiral centers,
Small peptide inhibitors of smooth muscle myosin light chain kinase
Gaeta,Lehman De Gaeta,Kogan,Or,Foster,Czarniecki
, p. 964 - 972 (2007/10/02)
The pentapeptide Ser-Asn-Val-Phe-Ala-OBzl has been identified as the smallest inhibitory peptide of myosin light chain kinase (MLCK) derived from the primary sequence of the light chain phosphorylation site. The specific contributions of individual amino
The 3,4-Dihydro-2H-pyran Approach to (+)-Milbemycin β3. Part 2. An Improved Synthesis of (2R,4S,6S,8R,9S)-2--8,9-dimethyl-4-(dimethyl-t-butylsilyloxy)-1,7-dioxaspiroundecane
Kocienski, Philip J.,Street, Stephen D. A.,Yeates, Clive,Campbell, Simon F.
, p. 2189 - 2194 (2007/10/02)
A more efficient synthesis of the title compound (2), previously used in a total synthesis of (+)-milbemycin β3 (1), is described.The key step in the sequence involves a nucleophilic cleavage of the oxirane (4) by the organocuprate derived from
