155346-00-2

Upstream product

• 87-72-9 L-xylopyranose 
• 218621-71-7 6-hydroxy-2,2-dimethyl-5-(4-methylphenylsulfonyloxymethyl)-(3aS,5S,6R,6aS)-perhydrofuro[2,3-d][1,3]dioxole 
• 100-39-0 benzyl bromide 
• 155345-99-6 (1S,2R,3S,5S)-7,7-dimethyl-4,6,8-trioxa-3-[(phenylmethoxy)methyl]bicyclo[3.3.0]octan-2-ol 

Downstream Products

• 268750-14-7 1,2-O-(1-methylethylidene)-3-deoxy-3-(hydroxymethyl)-5-O-benzyl-L-ribofuranose 
• 155346-02-4 (1S,5S,7S,8S)-3,3-dimethyl-2,4,6-trioxa-7-[(phenylmethoxy)methyl]spiro[bicyclo[3.3.0]octane-8,5'-oxolane]-10-one 
• 261357-48-6 (5R)-5-(hydroxymethyl)-5-[(1S)-1-hydroxy-2-(phenylmethoxy)ethyl]oxolan-2-one 
• 155346-01-3 (1S,2S,3S,5S)-2-(3-hydroxypropyl)-7,7-dimethyl-4,6,8-trioxa-3-[(phenylmethoxy)methyl]bicyclo[3.3.0]octan-2-ol 
• 268750-13-6 1,2-O-(1-methylethylidene)-3-deoxy-3-methylene-5-O-benzyl-L-xylofuranose 

Relevant academic research and scientific papers

Synthesis of L-3'-hydroxymethylribonucleosides

The target compounds were synthesized via the key intermediate carbohydrate 8, which was synthesized by first selectively protecting the 1'- and 2'- hydroxyl groups followed by selective tosylation of the 5'-hydroxyl group to obtain compound 3. The tosyl

Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?

The design of potent protein kinase C (PK-C) ligands with low nanomolar binding affinities was accomplished by the combined use of pharmacophore- and receptor-guided approaches based on the structure of the physiological enzyme activator, diacylglycerol (