155345-99-6

Upstream product

• 20194-18-7 sodium phenyl-methanolate 
• 218621-71-7 6-hydroxy-2,2-dimethyl-5-(4-methylphenylsulfonyloxymethyl)-(3aS,5S,6R,6aS)-perhydrofuro[2,3-d][1,3]dioxole 
• 100-44-7 benzyl chloride 
• 114861-22-2 1,2-O-isopropylidene-α-L-xylofuranose 
• 87-72-9 L-xylopyranose 
• 100-39-0 benzyl bromide 

Downstream Products

• 864858-18-4 5-O-benzyl-1,2-O-isopropylidene-3-O-triflyl-α-L-xylofuranose 
• 268750-14-7 1,2-O-(1-methylethylidene)-3-deoxy-3-(hydroxymethyl)-5-O-benzyl-L-ribofuranose 
• 268750-13-6 1,2-O-(1-methylethylidene)-3-deoxy-3-methylene-5-O-benzyl-L-xylofuranose 
• 155346-01-3 (1S,2S,3S,5S)-2-(3-hydroxypropyl)-7,7-dimethyl-4,6,8-trioxa-3-[(phenylmethoxy)methyl]bicyclo[3.3.0]octan-2-ol 
• 155346-02-4 (1S,5S,7S,8S)-3,3-dimethyl-2,4,6-trioxa-7-[(phenylmethoxy)methyl]spiro[bicyclo[3.3.0]octane-8,5'-oxolane]-10-one 
• 261357-48-6 (5R)-5-(hydroxymethyl)-5-[(1S)-1-hydroxy-2-(phenylmethoxy)ethyl]oxolan-2-one 
• 864858-33-3 (1S,3S,4R,5S)-1-[(benzyloxy)methyl]-3-methoxy-2-oxabicyclo[3.1.0]hex-4-yl acetate 
• 864858-24-2 [(3aS,4aS,5aS,5bS)-2,2-dimethyltetrahydro-4aH-cyclopropa[4,5]furo[2,3-d][1,3]dioxol-4a-yl]methyl benzyl ether 
• 864858-30-0 (1S,3S,4R,5S)-1-[(benzyloxy)methyl]-3-methoxy-2-oxabicyclo[3.1.0]hexan-4-ol 
• 864858-27-5 (1S,3S,4S,5S)-1-[(benzyloxy)methyl]-3-methoxy-2-oxabicyclo[3.1.0]hexan-4-ol 
• 864858-21-9 [(3aS,6aS)-2,2-dimethyl-3a,6a-dihydrofuro[2,3-d][1,3]dioxol-5-yl]methyl benzyl ether 
• 155346-00-2 (1R,3S,5S)-7,7-dimethyl-4,6,8-trioxa-3-[(phenylmethoxy)methyl]bicyclo[3.3.0]octan-2-one 

Relevant academic research and scientific papers

Novel L-xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes

The prevalence of diabetes throughout the world continues to increase and has become a major health issue. Recently there have been several reports of inhibitors directed toward the sodium-dependent glucose cotransporter 2 (SGLT2) as a method of maintaining glucose homeostasis in diabetic patients. Herein we report the discovery of the novel O-xyloside 7c that inhibits SGLT2 in vitro and urinary glucose reabsorption in vivo. 2009 American Chemical Society.

Synthesis of L-3'-hydroxymethylribonucleosides

The target compounds were synthesized via the key intermediate carbohydrate 8, which was synthesized by first selectively protecting the 1'- and 2'- hydroxyl groups followed by selective tosylation of the 5'-hydroxyl group to obtain compound 3. The tosyl

Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?

The design of potent protein kinase C (PK-C) ligands with low nanomolar binding affinities was accomplished by the combined use of pharmacophore- and receptor-guided approaches based on the structure of the physiological enzyme activator, diacylglycerol (