15536-71-7

Usage

InChI:InChI=1/C10H18O/c1-10(2,3)7-4-5-8-9(6-7)11-8/h7-9H,4-6H2,1-3H3

Upstream product

• 2228-98-0 4-tert-butylcylohexene 
• 66228-04-4 r-5-tert-Butyl-c-2-(trimethylsilyl)cyclohexan-t-ol 
• 111324-97-1 r-5-tert-Butyl-t-1-(trimethylsilyloxy)-c-2-(trimethylsilyl)cyclohexane 
• 14753-40-3 trans-1,2-Epoxy-4-tert-butylcyclohexane 

Downstream Products

• 118787-35-2 (4aS,26aS)-2-tert-Butyl-icosahydro-5,8,11,14,17,20,23,26-octaoxa-benzocyclotetracosene 
• 71962-02-2 (1S,2S,4R)-(+)-tert-Butylcyclohexane-1,2-diol 
• 71962-03-3 (1R,2R,4S)-(-)-tert-Butylcyclohexane-1,2-diol 
• 2228-98-0 4-tert-butylcylohexene 
• 7076-92-8 cis-4-tert-Butyl-trans-2-methyl-cyclohexyl-p-toluolsulfonat 
• 86509-66-2 tert-Butylperoxy-oxo-acetic acid (1S,2S,4R)-4-tert-butyl-2-methyl-cyclohexyl ester 
• 66820-12-0 (1R,3S)-1-tert-Butyl-3,5-dimethyl-cyclohexane 
• 86509-69-5 tert-Butylperoxy-oxo-acetic acid (1S,2S,5R)-5-tert-butyl-2-methyl-cyclohexyl ester 
• 31927-14-7 t-5-t-butyl-r-3-methylcyclohexene 
• 27003-39-0 r-1-t-butyl-t-3-methylcyclohexane 
• 15822-50-1 5-t-butyl-1-methylcyclohexene 
• 142744-01-2 r-4-tert-Butyl-t-2-(trimethylsilyl)cyclohex-c-yl 3,5-dinitrobenzoate 
• 142744-00-1 r-4-tert-Butyl-t-2-(trimethylsilyl)cyclohex-c-yl p-nitrobenzoate 
• 1138-51-8 di-tert-butyl-3,5 cyclohexanone-trans 

Relevant academic research and scientific papers

Exploration of trans-2-(azaarylsulfanyl)-cyclohexanols as potential pH-triggered conformational switches

A series of trans-2-(azaarylsulfanyl)-cyclohexanols, structurally similar to previously studied trans-2-aminocylohexanols, have been synthesized and explored as conformational pH triggers. 1H NMR spectroscopy was used to estimate the position of the chair-chair conformational equilibrium and its acid-induced shift towards the conformer with the azaarylsulfanyl and hydroxy groups in equatorial positions due to an intramolecular hydrogen bond and electrostatic interactions. Such acid-induced transition may be used to control the geometry-dependent molecular properties. The 1H NMR titration curves were used for estimation of the pKa values of protonated compounds that varied from 2.8 to 4.3 (in d4-methanol) depending on the structure of the azaarylsulfanyl group.

Chlorohydroxylation of Olefins with Peroxides and Titanium Tetrachloride

TiCl4/TBHP (DTBP) is a powerful reagent for the direct chlorohydroxylation of olefins.Moderate diastereoselectivity has been observed in the reaction of chiral substrates bearing allylic or homoallylic substituents.

Convenient synthesis of 1,3-dithiolane-2-thiones: Cyclic trithiocarbonates as conformational locks

A series of novel 1,3-dithiolane-2-thiones, or cyclic trithiocarbonates, has been prepared by a new simple procedure: a treatment of the corresponding epoxides with the commercially available potassium ethyl xanthogenate, KSC(S)OEt. The stereochemistry of the products was determined by 1H NMR and in some cases by single-crystal X-ray data. Cyclohexane-based 1,3- dithiolane-2-thiones revealed a trans-fusion of the carbo- and hetero-cycles. The products obtained from the mono-substituted cyclohexene oxides demonstrated an axial position of the substituents. Thus the epoxide transformation into trithiocarbonate can be used as a method for locking cyclic compounds in unstable conformations.ARKAT-USA, Inc.

Oxidative Displacement of Hypervalent Iodine from Alkyl Iodides

Oxidative displacement of iodine from primary alkyl iodides and vic-substituted iodocyclohexanes with m-chloroperbenzoic acid in either dichloromethane or t-butyl alcohol-water gives primary alcohols and vic-substituted cyclohexanols, respectively.Retention of configuration at the displacement centre occurs for all of the trans-vic-substituted iodocyclohexanes except the iodoacetate and iodotrifluoroacetate where inversion of configuration occurs to give cis-hydroxy-esters.Oxidation of (S)-2-iodo-octane occurs with almost complete inversion to give (R)-octan-2-ol but also affords octan-1-ol, octan-3-ol, and octan-2-one.