66228-04-4

Basic information

• Product Name: cis-1-(trimethylsilyl)-trans-4-tert-butylcyclohexan-2-ol
• Synonyms: cis-1-(trimethylsilyl)-trans-4-tert-butylcyclohexan-2-ol
• CAS NO: 66228-04-4
• Molecular Weight: 228.45
• Mol File: 66228-04-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: cis-1-(trimethylsilyl)-trans-4-tert-butylcyclohexan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: cis-1-(trimethylsilyl)-trans-4-tert-butylcyclohexan-2-ol(66228-04-4)
• EPA Substance Registry System: cis-1-(trimethylsilyl)-trans-4-tert-butylcyclohexan-2-ol(66228-04-4)

Safety Data

• Hazardous Substances Data: 66228-04-4(Hazardous Substances Data)

Upstream product

• 14753-40-3 trans-1,2-Epoxy-4-tert-butylcyclohexane 
• 111324-97-1 r-5-tert-Butyl-t-1-(trimethylsilyloxy)-c-2-(trimethylsilyl)cyclohexane 
• 66255-13-8 1-(trimethylsilyl)-4-tert-butyl-7-oxa-cis-bicyclo<4.1.0>heptane 
• 98-53-3 4-tercbutyl-cyclohexanone 
• 63031-67-4 4-(1,1-dimethylethyl)cyclohexen-1-yltrimethylsilane 
• 6832-09-3 1-chloro-4-tert-butylcyclohexene 

Downstream Products

• 15536-71-7 3-tert-butyl-7-oxabicyclo<4.1.0>heptane 
• 142743-99-5 r-5-tert-Butyl-c-2-(trimethylsilyl)cyclohex-t-yl p-nitrobenzoate 
• 142743-99-5 r-5-tert-Butyl-c-2-(trimethylsilyl)cyclohex-c-yl p-nitrobenzoate 
• 936-99-2 3-tert-butylcyclohexanone 
• 142743-99-5 r-5-tert-Butyl-t-2-(trimethylsilyl)cyclohex-t-yl p-nitrobenzoate 
• 2228-98-0 4-tert-butylcylohexene 

Relevant articles and documents

Stereoelectronic Effect of the Trimethylsilyl Substituent upon C-O Bond Lengths at the β Position: Some Structural Studies

Results of low-temperature (130 K) crystal structure analyses for seven β-trimethylsilyl-substituted cyclohexylnitrobenzoate esters are reported.For those molecules (three) with the Si-C and C-O bonds antiperiplanar the C-O bond lengths are increased by 0

Silanes in Organic Synthesis. 9. Enesilylation as a Method for 1,2-Carbonyl Migration within Ketones and for Conversion to 1,2-Transposed Allylic Alcohols

Vinylsilanes are shown to be valuable synthetic intermediates in useful transformations of ketones.The epoxidation of vinylsilanes followed by lithium aluminium hydride reduction and oxidation with chromic acid and sulfuric acid in a two-phase (ether/water) system often gives high yields of 1,2-transposed ketones.With singlet oxygen and sequential sodium borohydride reduction, 2-trimethylsilyl alcohols are produced in which the α position of the parent ketone has been regiospecifically oxygenated.Fluoride ion promoted desilylation completes the conversion to the migrated allylic alcohol.