155375-91-0Relevant academic research and scientific papers
Azoles and azines. XCIX. some reactions of oxo derivatives of 5,5′-ylidenedipyrimidines and 5H-pyrano[2,3-d:6,5-d′]dipyrimidines
Moskvin,Petrova,Krasnov,Ivin
, p. 803 - 810 (2007/10/03)
5,5′-Alkylidene(arylmethylene)dipirimidin-4,4′,6,6′- tetraols and 5-alkyl(aryl)-5H-pyrano-[2,3-d:6,5-d′]dipyrimidine-4,6(3H,7H)-diones react with POCl3, yielding mainly 4,6-dichloro-5H-pyrano-[2,3-d:6,5-d′]dipyrimidines. The chlorine atoms in the latter compounds are readily replaced by the action of nucleophiles, such as sodium methoxide and benzylamine. Hydrogen sulfite ion adds at C2 of 5,5′-alkylidene-(arylmethylene)dipyrimidine-4,4′,6,6′- tetraols. Barbituric acid also attacks position 2 of the pyrimidine ring, resulting in decomposition of the substrate to give 5-aminomethylenebarbituric acid or its derivatives. Alkylation of 5-alkyl(aryl)-5H-pyrano[2,3-d:6,5-d′]dipyrimidine-4,6(3H,7H)-diones with dimethyl sulfate and methyl iodide occurs at the nitrogen atoms, whereas diazomethane reacts at both nitrogen and oxygen atoms.
AZINES AND AZOLES. LXXXVIII. CONDENSATION OF 4,6-DIHYDROXYPYRIMIDINE WITH AROMATIC ALDEHYDES
Moskvin, A. V.,Petrova, N. M.,Semenova, E. A.,Shopova, M.,Gindin, V. A.,Ivin, B. A.
, p. 1454 - 1459 (2007/10/02)
4,6-Dihydroxypyrimidine in water and in pyridine is condensed with aromatic aldehydes to give 5,5'-arylmethylenebis(4,6-dihydroxypyrimidines).When carried out in acetic acid in the presence of acetic anhydride this reaction results in the formation of 9-a
