27402-47-7

Basic information

• Product Name: BENZALBARBITURIC ACID
• Synonyms: BUTTPARK 9\02-27;BENZALBARBITURIC ACID;5-BENZYLIDENEBARBITURIC ACID;5-(Phenylmethylene)-2,4,6(1H,3H,5H)-pyrimidinetrione;Hexahydro-5-benzylidenepyrimidine-2,4,6-trione;5-BENZYLIDENE-PYRIMIDINE-2,4,6-TRIONE;5-benzylidenepyrimidine-2,4,6(1H,3H,5H)-trione
• CAS NO: 27402-47-7
• Molecular Formula: C₁₁H₈N₂O₃
• Molecular Weight: 216.19
• Mol File: 27402-47-7.mol
• Article Data: 76

Chemical Properties

• Melting Point: 256 °C
• Appearance: /
• Density: 1.387±0.06 g/cm3(Predicted)
• PKA: 7.17±0.20(Predicted)
• CAS DataBase Reference: BENZALBARBITURIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: BENZALBARBITURIC ACID(27402-47-7)
• EPA Substance Registry System: BENZALBARBITURIC ACID(27402-47-7)

Safety Data

• Hazardous Substances Data: 27402-47-7(Hazardous Substances Data)

Usage

General Description

Benzalbarbituric acid, also known as malonylurea or malonylmalonamide, is a chemical compound with the molecular formula C10H8N2O3. It is a white crystalline solid that is insoluble in water and commonly used in the synthesis of pharmaceuticals and dyes. Benzalbarbituric acid functions as a precursor to barbituric acid derivatives, which have sedative properties and are used for their hypnotic and anticonvulsant effects. Additionally, it is utilized in the production of metal complexes and as a building block for the synthesis of heterocyclic compounds. Its unique chemical properties and versatility make it a valuable component in various industrial applications.

Upstream product

• 108-24-7 acetic anhydride 
• 407-25-0 trifluoroacetic anhydride 
• 873-83-6 4-Amino-2,6-dihydroxypyrimidine 
• 100-52-7 benzaldehyde 
• 2700-22-3 Benzylidenemalononitrile 
• 67-52-7 BARBITURIC ACID 
• 3376-23-6 N-methyl-α-phenylnitrone 
• 1122-58-3 dmap 
• 105-36-2 ethyl bromoacetate 
• 110-86-1 pyridine 
• 7732-18-5 water 
• 141-82-2 malonic acid 
• 57-13-6 urea 
• 5292-53-5 diethyl benzalmalonate 

Downstream Products

• 186503-93-5 5-[1-phenyl-2-(3-chlorophenyl)ethyl]barbituric acid 
• 59025-32-0 5-aminomethylenebarbituric acid 
• 155375-91-0 4,4',6,6'-tetrahydroxy-5,5'-benzylidenedipyrimidine 
• 35173-74-1 3,3'-bis-indolyl(phenyl)methane 
• 17371-59-4 2-methyl-3-((2-methyl-1H-indol-3-yl)(phenyl)methyl)-1H-indole 
• 1206694-35-0 (2,4,6-trioxo-1,2,3,4,5,6-hexahydropyrimidin-5-yl)[2-(5-hydroxy-3-methylpyrazol-1-yl)-6-methyl-4-oxo-3,4-dihydropyrimidin-5-yl]phenylmethane 
• 1361480-20-7 C₃₃H₂₆N₄O₄ 
• 1361480-29-6 C₂₉H₂₆N₄O₅ 
• 2700-22-3 Benzylidenemalononitrile 
• 27845-50-7 (E)-N-benzylidenebenzylamine 
• 67-52-7 BARBITURIC ACID 
• 100-52-7 benzaldehyde 

Relevant articles and documents

A method for rapid synthesis of 18Olabeled aldehyde compounds

The present invention discloses a method for rapid synthesis of 18O labeled aldehyde compounds, first the aldehyde compound and barbituric acid was added to ethanol, reacted at 40 ~ 60 ° C for 10 to 12 h, to obtain precipitation, cooled to room

Knoevenagel condensation in aqueous media promoted by 2,2′-bipyridinium dihydrogen phosphate as a green efficient catalyst

A 2,2′-Bipyridine-based ionic compound named 2,2′-bipyridinium dihydrogen phosphate was synthesized by addition of phosphoric acid to a solution of 2,2′-Bipyridine in dichloromethane. After the characterization using FT-IR, mass, 1H, 13C and 31P NMR techniques, it was used as a Bronsted dicationic acidic catalyst for the promotion of the synthesis of 2-arylidene malononitrile and 5-arylidene barbituric acid derivatives via Knoevenagel condensation reaction in water. Some of the advantages of this method are the utilization of an easy preparable, cost-effective and eco-friendly organic salt as a catalyst within high rates and yields of the reactions, simple and quick work-up and acceptable reusability of the catalyst.

Three Resorcin[4]arene-Based Two-Dimensional Zn(II) Supramolecular Isomers Synthesized via a Structure-Directing Strategy for Knoevenagel Condensation

Herein, in the presence of three structure-directing agents (SDAs), a family of imidazole-functionalized resorcin[4]arene-based coordination polymers (CPs), [Zn(TIC4R)(HCOO)]·HCOO·0.5DMF·1.5H2O (1), [Zn(TIC4R)(CN)]·HCOO·DMF·2.5H2O (2), and [Zn(TIC4R)(H2O)