155431-86-0

Basic information

• Product Name: 4-(4-chlorophenyl)-2-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3(2H,4H)-1,2,4-triazolone
• CAS NO: 155431-86-0
• Molecular Weight: 377.778
• Mol File: 155431-86-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-(4-chlorophenyl)-2-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3(2H,4H)-1,2,4-triazolone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-chlorophenyl)-2-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3(2H,4H)-1,2,4-triazolone(155431-86-0)
• EPA Substance Registry System: 4-(4-chlorophenyl)-2-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3(2H,4H)-1,2,4-triazolone(155431-86-0)

Safety Data

• Hazardous Substances Data: 155431-86-0(Hazardous Substances Data)

Upstream product

• 150802-96-3 (2S,3R)-3-(2,4-Difluorophenyl)-3,4-epoxy-2-butanol 
• 5097-86-9 4-(4-chlorophenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 126918-33-0 (1S)-1-<(2R)-2-(2,4-difluorophenyl)-2-oxiranyl>ethanol 

Relevant articles and documents

Efficient one-step synthesis of a key intermediate for the synthesis of azole antifungals using the Mitsunobu protocol

A simple and single-step process for coupling (2R,1S)-1-[2-(2,4- difluorophenyl)-2-oxiranyl]ethanol and various 1,2,4-triazolones utilizing the Mitsunobu protocol is described. The product so formed is a key intermediate in the synthesis of azole antifung