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126918-33-0

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126918-33-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 126918-33-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,9,1 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 126918-33:
(8*1)+(7*2)+(6*6)+(5*9)+(4*1)+(3*8)+(2*3)+(1*3)=140
140 % 10 = 0
So 126918-33-0 is a valid CAS Registry Number.

126918-33-0Downstream Products

126918-33-0Relevant articles and documents

METHOD FOR PRODUCING TRIAZOLE COMPOUND

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, (2018/09/21)

PROBLEM TO BE SOLVED: To provide a novel method for producing a triazole compound useful as a pharmaceutical intermediate. SOLUTION: A production method includes reacting a lactic acid derivative with thionyl chloride, then reacting it with 1,3-difluoro benzene in the presence of Al chloride to obtain a ketone derivative, which is turned into an olefin with a Wittig reagent to be derived into compound (2), and it is then turned into an epoxy and a triazole to be derived into compound (1). SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Production methods of epoxytriazole derivative and intermediate therefor

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Page 9, (2010/11/30)

An epoxytriazole derivative (V) useful as an intermediate for anti-fungal agents and an intermediate therefor having high quality can be produced economically and efficiently by the following industrial means. A compound of the following formula (I) is reacted with trimethyloxosulfonium salt and the like in the presence of a base to give compound (II), this compound is converted to compound (IV), and this compound is reacted with 1,2,4-triazole in the presence of a base. wherein Ar is a phenyl group optionally substituted by 1 to 3 halogen atom(s) or trifluoromethyl group, R is a hydrogen atom or lower alkyl group, and X is a leaving group.

Triazole antifungals. III. Stereocontrolled synthesis of an optically active triazolylmethyloxirane precursor to antifungal oxazolidine derivatives

Konosu,Miyaoka,Tajima,Oida

, p. 2241 - 2246 (2007/10/02)

Stereocontrolled synthesis of an optically active triazolylmethyloxirane 2, an important intermediate for the preparation of antifungal oxazolidine compounds 1, was achieved by two methods using L-lactic acid as a starting material. The key intermediate ketone 6 used in the procedures also served for the synthesis of the enantiomer of 2 and the corresponding diastereomeric epoxide.

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