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155495-82-2

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155495-82-2 Usage

General Description

4-(Trifluoromethyl)quinoline-3-carboxylic acid is a chemical compound with the molecular formula C11H6F3NO2. It is a quinoline derivative, containing a trifluoromethyl group and a carboxylic acid functional group. 4-(TRIFLUOROMETHYL)QUINOLINE-3-CARBOXYLIC ACID is considered as a potential building block for the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and pharmacological properties. It is also used as a key intermediate in the synthesis of various bioactive compounds and has potential applications in the fields of medicinal chemistry and drug discovery. However, further research is needed to fully understand its potential uses and properties.

Check Digit Verification of cas no

The CAS Registry Mumber 155495-82-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,5,4,9 and 5 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 155495-82:
(8*1)+(7*5)+(6*5)+(5*4)+(4*9)+(3*5)+(2*8)+(1*2)=162
162 % 10 = 2
So 155495-82-2 is a valid CAS Registry Number.

155495-82-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(Trifluoromethyl)quinoline-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 4-(trifluoromethyl)quinoline-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:155495-82-2 SDS

155495-82-2Downstream Products

155495-82-2Relevant articles and documents

INHIBITORS OF MALT1 AND USES THEREOF

-

, (2018/09/28)

Provided herein are compounds that inhibit MALTl, a protein whose activity is responsible for constitutive NF-κΒ signaling in certain cancers (e.g., activated B-cell diffuse large B-cell lymphoma (ABC-DLBCL)). Also provided are pharmaceutical compositions and kits comprising the compounds, and methods of treating MALTl -related diseases and disorders (e.g., cancer) with the compounds in a subject, by administering the compounds and/or compositions described herein.

Recommendable routes to trifluoromethyl-substituted pyridine- and quinolinecarboxylic acids

Cottet, Fabrice,Marull, Marc,Lefebvre, Olivier,Schlosser, Manfred

, p. 1559 - 1568 (2007/10/03)

As part of a case study, rational strategies for the preparation of all ten 2-, 3-, or 4-pyridinecarboxylic acids and all nine 2-, 3-, 4-, or 8-quinolinecarboxylic acids bearing trifluoromethyl substituents at the 2-, 3-, or 4-position were elaborated. The trifluoromethyl group, if not already present in the precursor, was introduced either by the deoxygenative fluorination of suitable carboxylic acids with sulfur tetrafluoride or by the displacement of ring-bound bromine or iodine by trifluoromethylcopper generated in situ. The carboxy function was produced by treatment of organolithium or organomagnesium intermediates, products of halogen/metal or hydrogen/ metal permutation, with carbon dioxide. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).

Synthesis of some fluorinated nitrogen heterocycles from (diethylaminomethylene) hexafluoroacetylacetone (DAMFA)

Soufyane, Mustapha

, p. 7737 - 7740 (2007/10/02)

Simple and highly efficient syntheses of the title compounds from DAMFA are described in the quinoline, azepinonaphtalene, azaphenanthrene(s), pyridopyridine, pyrazole, pyrrole and pyrimidine series.

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