155595-12-3

Upstream product

• 68534-64-5 (1S,2S)-(+)-2-(benzylamino)-1-phenylpropane-1,3-diol 
• 100-44-7 benzyl chloride 
• 100-52-7 benzaldehyde 
• 195144-29-7 (1S,2S)-(+)-2-(benzylideneamino)-1-phenylpropane-1,3-diol 
• 28143-91-1 (1S,2S)-2-amino-1-phenyl-1,3-diol 
• 100-39-0 benzyl bromide 

Downstream Products

• 155595-16-7 methyl E-(5S,6S)-dibenzylamino-5-phenyl-7-triphenylmethoxy-4-thia-2-heptenoate 
• 155595-14-5 (1S,2S)-N-<(1-chloro-1-phenyl-3-triphenylmethoxy)propyl-2>dibenzylamine 
• 155595-13-4 (1S,2S)-2-dibenzylamino-1-phenyl-3-triphenylmethoxy-1-propane-1-thiol 
• 155595-23-6 (1S,4S,5R,7S,8S)-2-benzyl-8-dibenzylamino-4-methoxycarbonyl-7-phenyl-3-oxa-6-thia-2-azabicyclo<3.3.0>octane 
• 155595-15-6 methyl E-(5S,6S)-dibenzylamino-7-hydroxy-5-phenyl-4-thia-2-heptenoate 
• 155595-11-2 (1S,2S)-2-dibenzylamino-1-phenyl-3-triphenylmethoxy-1-propanol 

Relevant academic research and scientific papers

Reaction of (1S,2S)-2-amino-1-phenyl-1,3-propanediol with thioacids under the Mitsunobu reaction condition

The Mitsunobu thioesterification was applied to the title 2-amino-1,3-propanediol (1). The regio- and stereochemistry of the reaction was investigated in correlation with the nature of substituents attached to the nitrogen.

Highly diastereoselective formation of bicyclic compounds by intramolecular cycloaddition of chiral thiaalkenyl nitrones

Starting from chiral mercapto alcohols 5 in several reaction steps nitrones 7 were formed which underwent spontaneously intramolecular cycloaddition to give diastereomerically pure products 8. However, during the reaction course partial racemization had o