1556-40-7

Basic information

• Product Name: N-(acridin-9-ylmethyl)benzylamine
• CAS NO: 1556-40-7
• Molecular Weight: 298.387
• Mol File: 1556-40-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(acridin-9-ylmethyl)benzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(acridin-9-ylmethyl)benzylamine(1556-40-7)
• EPA Substance Registry System: N-(acridin-9-ylmethyl)benzylamine(1556-40-7)

Safety Data

• Hazardous Substances Data: 1556-40-7(Hazardous Substances Data)

Upstream product

• 122-39-4 diphenylamine 
• 611-64-3 9-methyl-acridine 

Relevant articles and documents

Spontaneous cyclization of (acridin-9-ylmethyl)thioureas to spiro [dihydroacridine-9′(10′H),5-imidazolidine]-2-thiones, a novel type of acridine spirocycles

Novel acridine spirocompounds, spiro[dihydroacridine-9′(10′H), 5-imidazolidine]-2-thiones have been prepared by the spontaneous cyclization of 1-substituted 3-(acridin-9-ylmethyl)thioureas, which were obtained from 1-(acridin-9-yl)methanamine, N-(acridin-9-ylmethyl)propan-1-amine, and N-(acridin-9-ylmethyl)benzylamine and alkyl/aryl isothiocyanates, as continuation of our previous studies on new acridine spirocycles. Imidazolidine-2-thiones thus obtained were subsequently transformed with mesitylnitrile oxide to imidazolidine-2-one analogues, some of which partly reopened to the corresponding (acridin-9-ylmethyl)ureas. An unusual spirocyclization via a CH carbanion instead of the N-1 nitrogen has been found for 3-(acridin-9-ylmethyl)-1-(acridin-9-yl)thioureas possessing two acridine rings. Structural modifications in positions 1, 3, and 4 of the spiro ring together with 1H, 13C, and 15N NMR spectroscopy and X-ray crystallography have been employed to rationalize a general propensity of various 9-substituted acridines to undergo easy spirocyclization.