155666-33-4

Basic information

• Product Name: 2-AMINO-4-BENZYLOXY-5-METHOXY-BENZOIC ACID
• Synonyms: 2-AMINO-4-BENZYLOXY-5-METHOXY-BENZOIC ACID;2-Amino-5-methoxy-4-(phenylmethoxy)-benzoic acid;4-Benzyloxy-5-methoxyanthranilic acid
• CAS NO: 155666-33-4
• Molecular Formula: C₁₅H₁₅NO₄
• Molecular Weight: 273.28
• Product Categories: pharmacetical
• Mol File: 155666-33-4.mol
• Article Data: 10

Chemical Properties

• Melting Point: 159-161℃
• Boiling Point: 462.536°C at 760 mmHg
• Flash Point: 233.534°C
• Appearance: /
• Density: 1.283±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 2.34±0.10(Predicted)
• CAS DataBase Reference: 2-AMINO-4-BENZYLOXY-5-METHOXY-BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-BENZYLOXY-5-METHOXY-BENZOIC ACID(155666-33-4)
• EPA Substance Registry System: 2-AMINO-4-BENZYLOXY-5-METHOXY-BENZOIC ACID(155666-33-4)

Safety Data

• Hazardous Substances Data: 155666-33-4(Hazardous Substances Data)

Usage

General Description

2-AMINO-4-BENZYLOXY-5-METHOXY-BENZOIC ACID is a chemical compound with the molecular formula C16H15NO4. It is a derivative of benzoic acid and contains an amino group, a benzyl group, and a methoxy group. 2-AMINO-4-BENZYLOXY-5-METHOXY-BENZOIC ACID is commonly used in the synthesis of pharmaceuticals and other organic compounds. It has potential biological activity and may have applications in the development of new drugs. The compound's structure and properties make it a versatile building block in organic synthesis and medicinal chemistry.

InChI:InChI=1/C15H15NO4/c1-19-13-7-11(15(17)18)12(16)8-14(13)20-9-10-5-3-2-4-6-10/h2-8H,9,16H2,1H3,(H,17,18)

Upstream product

• 166117-56-2 2′-azido-4′-(benzyloxy)-5′-methoxybenzoic acid 
• 61032-42-6 methyl 2-amino-4-(benzyloxy)-5-methoxybenzoate 
• 60547-92-4 4-(benzyloxy)-5-methoxy-2-nitrobenzoic acid 
• 56441-97-5 methyl 4-(benzyloxy)-3-methoxybenzoate 
• 1486-53-9 4-(benzyloxy)-3-methoxybenzoic acid 
• 61032-41-5 methyl 4-(benzyloxy)-5-methoxy-2-nitrobenzoate 

Downstream Products

• 253777-45-6 7-benzyloxy-6-methoxyisatoic anhydride 
• 849795-72-8 (11aS)-8-benzyloxy-7-methoxy-1,2,3,9,10,11,11a-hexahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one 
• 253777-44-5 N-allyl-7-benzyloxy-6-methoxyisatoic anhydride 
• 253777-50-3 8-benzyloxy-4-(3-bromopropyl)-7-methoxy-1-trifluoroacetyl-1,4-dihydrobenzo[e][1,4]diazepin-5-one 
• 253777-48-9 2-(allyl-trifluoroacetyl)-amino-4-benzyloxy-N-3-(bromopropyl)-5-methoxy-benzamide 
• 166117-56-2 2′-azido-4′-(benzyloxy)-5′-methoxybenzoic acid 

Relevant articles and documents

Condensation of anthranilic acids with pyridines to furnish pyridoquinazolones via pyridine dearomatization

The unprecedented carbodiimide-mediated condensation between pyridines and anthranilic acids via pyridine dearomatization at room temperature has been developed to provide a straightforward approach to pyridoquinazolones. The value of this approach has further been demonstrated by its application to one-step, gram-scale syntheses of a series of pyridoquinazolone-based natural products and their analogues from readily available starting materials.

SYNTHESIS OF PYRROLO[2,1-C][1,4]BENZODIAZEPINE ANALOGUES

The present invention provides an efficient process for the preparation of pyrrolo[2,1-c][1,4]benzodiazepines (PBDS) represented by the formula (I): which starts from a substituted 2-amino benzoic acid compound, and involves a step of reduction of an inte

An efficient synthesis of pyrrolo[2,1-c][1,4]benzodiazepine. Synthesis of the antibiotic DC-81

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