56441-97-5

Basic information

• Product Name: METHYL 4-BENZYLOXY-3-METHOXYBENZOATE
• Synonyms: METHYL BENZYL VANILLATE;METHYL 4-BENZYLOXY-3-METHOXYBENZOATE;RARECHEM AL BF 0064;Benzoic acid, 3-Methoxy-4-(phenylMethoxy)-, Methyl ester;4-Benzyloxy-3-Methoxybenzoic Acid Methyl Ester;-3-methoxybenzoate;Methyl 4-(benzyloxy)
• CAS NO: 56441-97-5
• Molecular Formula: C₁₆H₁₆O₄
• Molecular Weight: 272.3
• Product Categories: Aromatic Esters
• Mol File: 56441-97-5.mol
• Article Data: 40

Chemical Properties

• Boiling Point: 400.12 °C at 760 mmHg
• Flash Point: 176.641 °C
• Appearance: /
• Density: 1.154 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: DCM, Ethyl Acetate
• CAS DataBase Reference: METHYL 4-BENZYLOXY-3-METHOXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-BENZYLOXY-3-METHOXYBENZOATE(56441-97-5)
• EPA Substance Registry System: METHYL 4-BENZYLOXY-3-METHOXYBENZOATE(56441-97-5)

Safety Data

• Hazardous Substances Data: 56441-97-5(Hazardous Substances Data)

Usage

Uses

4-Benzyloxy-3-methoxybenzoic Acid Methyl Ester is an intermediate in the synthesis of Clomiphene (C587025), an synthetic estrogen agonist-antagonist.

Upstream product

• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 
• 100-39-0 benzyl bromide 
• 67-56-1 methanol 
• 1486-53-9 4-(benzyloxy)-3-methoxybenzoic acid 
• 121-34-6 3-methoxy-4-hydroxybenzoic acid 
• 74-88-4 methyl iodide 
• 100-44-7 benzyl chloride 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 
• 121-33-5 vanillin 

Downstream Products

• 51908-43-1 1-(4-Benzyloxy-3-methoxy-phenyl)-2-methanesulfonyl-ethanone 

Relevant articles and documents

COMPOSITIONS AND METHODS RELATED TO MOLECULAR CONJUGATION

The invention relates to activated Michael acceptor (AMA) compounds that can undergo conjugation with biomolecules containing Michael donor moieties, thereby providing plasma-stable antibody-drug conjugates (ADCs). Pharmaceutical compositions of the ADCs are disclosed as well. Also provided herein are a number of applications (e.g., therapeutic applications) in which the compositions are useful.

FUSED HETEROCYCLIC BENZODIAZEPINE DERIVATIVES AND USES THEREOF

The present disclosure provides compounds and compositions capable of extending lifespan, and methods of use thereof.

Heterocyclic compound, preparation method and application thereof

The invention relates to a heterocyclic compound in the technical field of medicines. The compound is represented by a structural general formula I or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, X, Y, Z, Cy1, Cy2, m, n and t have the meanings given in the specification; in addition, the invention also discloses an application of the compound and the pharmaceuticallyacceptable salt thereof in preparation of drugs for treating diseases caused by abnormal high expression of tyrosine kinase, especially application in preparation of drugs for treating and preventingcancers.