155688-13-4Relevant academic research and scientific papers
Construction of a Chiral Quaternary Carbon Center via 1,2-Acyl Migration of an Optically Active α,β-Epoxy Ketone
Okada, Kunisuke,Katsura, Toshiyuki,Tanino, Hideo,Kakoi, Hisae,Inoue, Shoji
, p. 157 - 160 (1994)
The construction of a chiral building block with a quaternary carbon center is described, based on the Lewis acid-catalyzed acyl migration of α,β-epoxy ketone with alkyl and alkenyl substituents.
Simple and versatile synthesis of branched polyols: (+)-2-C-methylerythritol and (+)-2-C-methylthreitol
Fontana,Messina,Spinella,Cimino
, p. 7559 - 7562 (2007/10/03)
The paper reports a new approach for the enantioselective synthesis of 2-C-methyl tetrols. The procedure has been utilized for preparing methylthreitol and methylerythritol, a putative intermediate in the mevalonate-independent biosynthesis of terpenoids in bacteria, algae and higher plants. The methodology offers straightforward access to related compounds and isotopically labeled derivatives. (C) 2000 Elsevier Science Ltd.
