310887-98-0 Usage
Description
(2E)-3-Methyl-4-(benzyloxy)-2-butenoic Acid Methyl Ester is a colorless oil that serves as a crucial reactant in the synthesis of various organic compounds, particularly in the preparation of (+)-2-C-Methyl-D-erythritol-4-phosphate and branched polyols such as methylerythritol and methylthreitol. These compounds are significant as they act as synthons for the production of terpenoids, a diverse class of naturally occurring organic chemicals derived from isoprene units.
Uses
Used in Pharmaceutical Industry:
(2E)-3-Methyl-4-(benzyloxy)-2-butenoic Acid Methyl Ester is used as a reactant for the preparation of (+)-2-C-Methyl-D-erythritol-4-phosphate, which is an essential compound in the biosynthesis of isoprenoids. These isoprenoids play a vital role in various biological processes, including cell signaling, immune response, and the development of several diseases. Therefore, this ester is crucial in the development of pharmaceuticals targeting these pathways.
Used in Chemical Synthesis:
(2E)-3-Methyl-4-(benzyloxy)-2-butenoic Acid Methyl Ester is used as a reactant in the synthesis of branched polyols, such as methylerythritol and methylthreitol. These polyols are valuable intermediates in the production of various chemicals, including those used in the fragrance, flavor, and agrochemical industries. The ester's role in these syntheses highlights its importance in the chemical industry.
Used in the Production of Terpenoids:
(2E)-3-Methyl-4-(benzyloxy)-2-butenoic Acid Methyl Ester is used as a synthon for the production of terpenoids, which are a diverse group of organic compounds found in plants, insects, and marine organisms. Terpenoids have a wide range of applications, including their use as flavors, fragrances, pharmaceuticals, and biofuels. The ester's role in the synthesis of these compounds makes it an essential component in the development of various products across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 310887-98-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,0,8,8 and 7 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 310887-98:
(8*3)+(7*1)+(6*0)+(5*8)+(4*8)+(3*7)+(2*9)+(1*8)=150
150 % 10 = 0
So 310887-98-0 is a valid CAS Registry Number.
310887-98-0Relevant articles and documents
Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol and 2-C-methyl-D-erythritol-4-phosphate.
Koppisch, Andrew T,Poulter, C Dale
, p. 5416 - 5418 (2007/10/03)
2-C-Methyl-D-erythritol 4-phosphate (MEP, 2) and 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDPME, 3) are metabolites in the MEP pathway for biosynthesis of isoprenoid compounds in bacteria, plant chloroplasts, and algae. The free phosphoacid of 2 was prepared from benzyloxyacetone in five steps with an overall yield of 27% and an enantiomeric ratio (er) of 75:25. Following titration to the corresponding tributylammonium salt, 2 was coupled to cytidine 5'-monophosphate using a protocol originally developed for synthesis of base-sensitive nucleoside diphosphate sugars to give 3 in 40% yield, following purification by size exclusion chromatography.
Simple and versatile synthesis of branched polyols: (+)-2-C-methylerythritol and (+)-2-C-methylthreitol
Fontana,Messina,Spinella,Cimino
, p. 7559 - 7562 (2007/10/03)
The paper reports a new approach for the enantioselective synthesis of 2-C-methyl tetrols. The procedure has been utilized for preparing methylthreitol and methylerythritol, a putative intermediate in the mevalonate-independent biosynthesis of terpenoids in bacteria, algae and higher plants. The methodology offers straightforward access to related compounds and isotopically labeled derivatives. (C) 2000 Elsevier Science Ltd.
