40835-18-5

Basic information

• Product Name: methyl (2E)-3-methyl-4-oxobut-2-enoate
• Synonyms: 2-butenoic acid, 3-methyl-4-oxo-, methyl ester, (2E)-; Methyl (2E)-3-methyl-4-oxobut-2-enoate
• CAS NO: 40835-18-5
• Molecular Formula: C₆H₈O₃
• Molecular Weight: 128.1259
• Mol File: 40835-18-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 197.908°C at 760 mmHg
• Flash Point: 77.732°C
• Density: 1.052g/cm³
• Vapor Pressure: 0.37mmHg at 25°C
• Refractive Index: 1.434
• CAS DataBase Reference: methyl (2E)-3-methyl-4-oxobut-2-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2E)-3-methyl-4-oxobut-2-enoate(40835-18-5)
• EPA Substance Registry System: methyl (2E)-3-methyl-4-oxobut-2-enoate(40835-18-5)

Safety Data

• Hazardous Substances Data: 40835-18-5(Hazardous Substances Data)

Usage

General Description

Methyl (2E)-3-methyl-4-oxobut-2-enoate, also known as methyl 3-methyl-4-oxo-2-butenoate, is a chemical compound with the molecular formula C6H8O3. It is a colorless liquid with a fruity odor and is commonly used as a flavoring agent in the food and beverage industry. It is also used in the synthesis of pharmaceuticals and other organic compounds. Methyl (2E)-3-methyl-4-oxobut-2-enoate is considered to be relatively stable and non-reactive under normal conditions, but proper handling and storage procedures should still be followed to ensure safety. It is important to note that this compound should be used with care and in accordance with proper safety protocols to avoid any potential hazards.

Upstream product

• 13866-57-4 (E)-methyl 4-hydroxy-3-methylbut-2-enoate 
• 405897-14-5 dimethyl tartrate 
• 24720-64-7 2-(triphenylphosphoranylidene)propionaldehyde 
• 19041-17-9 methyl 4-bromo-3-methylbut-2-enoate 
• 82884-40-0 methyl 2-methyl-3-<(trimethylsilyl)oxy>-1-cyclopropanecarboxylate 
• 99016-62-3 (E)-3-Methyl-4-trimethylsilanyloxy-but-2-enoic acid methyl ester 
• 624-49-7 dimethylfumarate 
• 109745-70-2 methyl glyoxylate methyl hemi-acetal 
• 51043-49-3 (E)-1-(N-morpholino)propene 
• 109941-42-6 3-Methyl-4--crotonsaeuremethylester 
• 924-50-5 Methyl 3,3-dimethylacrylate 

Downstream Products

• 108734-51-6 3-((E)-6-Benzenesulfonyl-4-methyl-hex-4-enyl)-furan 
• 108742-77-4 5-[(5E,7E,9E)-13-Furan-3-yl-2,6,10-trimethyl-trideca-5,7,9-trien-(Z)-ylidene]-4-hydroxy-3-methyl-5H-furan-2-one 
• 63555-48-6 C₂₅H₃₂O₄ 
• 1355677-18-7 (S,E)-methyl 2-(4-(3-chlorobenzylidene)-1,3-dimethyl-5-oxocyclopent-2-enyl)acetate 
• 1355677-16-5 (S,E)-methyl 2-(4-(4-bromobenzylidene)-1,3-dimethyl-5-oxocyclopent-2-enyl)acetate 
• 1355677-15-4 (S,E)-methyl 2-(4-benzylidene-1,3-dimethyl-5-oxocyclopent-2-enyl)acetate 
• 1355676-93-5 (2E,4Z,6E)-methyl 7-(3-chlorophenyl)-6-formyl-3,5-dimethylhepta-2,4,6-trienoate 
• 1355676-89-9 (2E,4Z,6E)-methyl 7-(4-bromophenyl)-6-formyl-3,5-dimethylhepta-2,4,6-trienoate 
• 1355676-87-7 (2E,4Z,6E)-methyl 6-formyl-3,5-dimethyl-7-phenylhepta-2,4,6-trienoate 
• 57380-63-9 (2E,4E)-5-Cyclohex-1-enyl-3-methyl-penta-2,4-dienoic acid 
• 14398-42-6 (2E,4E)-3-methyl-5-(2,6,6-trimethylcyclohex-1-enyl)penta-2,4-dienoic acid 
• 103769-23-9 (E)-3-Methyl-4-oxo-but-2-enoic acid 2,4,4-trimethyl-3-vinyl-cyclohex-2-enyl ester 
• 144176-02-3 (4R,5R)-2,2,4-Trimethyl-5-phenyl-[1,2]oxasilolane-3-carboxylic acid methyl ester 
• 144176-02-3 (4R,5S)-2,2,4-Trimethyl-5-phenyl-[1,2]oxasilolane-3-carboxylic acid methyl ester 

Relevant articles and documents

The first synthesis of a noreremophilane isolated from the roots of Ligularia przewalskii

The total synthesis of a natural product noreremophilane has been achieved in just three steps from readily available starting materials. A highly stereo- and regio-selective Diels-Alder reaction was the key step in our synthesis.

Simple and versatile synthesis of branched polyols: (+)-2-C-methylerythritol and (+)-2-C-methylthreitol

The paper reports a new approach for the enantioselective synthesis of 2-C-methyl tetrols. The procedure has been utilized for preparing methylthreitol and methylerythritol, a putative intermediate in the mevalonate-independent biosynthesis of terpenoids in bacteria, algae and higher plants. The methodology offers straightforward access to related compounds and isotopically labeled derivatives. (C) 2000 Elsevier Science Ltd.

A Direct Route for the Synthesis of (E)-3-Alkyl-4-oxo-2-butenoic Acid Esters

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