155694-62-5Relevant academic research and scientific papers
Copper nanoparticles catalyzed economical synthesis of 3-substituted isocoumarins from 2-chlorobenzoic acids/amides and 1,3-diketones
Wang, Xiaowen,Wu, Chaolong,Sun, Youwen,Yao, Xiaoquan
, p. 3164 - 3167 (2017)
Copper nanoparticles were utilized as a highly efficient catalyst for a facile and economical synthesis of 3-substituted isocoumarins with 2-chlorobenzoic acids and 1,3-diketones as starting materials. The copper nanoparticles catalyst showed highly catalytic activity for the 2-chloro-substituted substrates to afford 3-substituted isocoumarins in good to excellent yields. Furthermore, good catalytic activity was also observed when 2-chlorobenzoic amides were utilized as substrates instead of the benzoic acids.
Synthesis of 3-substituted isocoumarins via a cascade intramolecular Ullmann-type coupling-rearrangement process
Ge, Zhi-Yuan,Fei, Xiang-Dong,Tang, Ting,Zhu, Yong-Ming,Shen, Jing-Kang
experimental part, p. 5736 - 5743 (2012/08/07)
A simple and highly efficient strategy for the synthesis of 3-substituted isocoumarins through a copper(I)-catalyzed reaction of 1-(2-halophenyl)-1,3- diones has been developed. The procedure is based on a cascade copper-catalyzed intramolecular Ullmann-type C-arylation and rearrangement process. This methodology is tolerant of a wide range of substrates and applicable to library synthesis.
Synthesis of Isocoumarin, 1-Isoquinolone and 4(1H)-Quinolone Derivatives via Seleno-intermediates
Izumi, Taeko,Morishita, Nobuya
, p. 145 - 152 (2007/10/02)
The reaction of 2-styrylbenzoic acid 2 with N-phenylselenosuccinimide (N-PPS) affords 3-phenyl-iso-coumarin derivatives 3 and 3,4-dihydro-3-phenyl-4-(phenylseleno)isocoumarins 4 via selenolactonization.The reaction of 2-styrylbenzamides 5 and 1-(2-aminoph
