155730-44-2

Upstream product

• 61739-41-1 (2R,4S,5R)-2-Chloro-3,4-dimethyl-5-phenyl-1,3,2-oxazaphospholidine 
• 4039-32-1 lithium hexamethyldisilazane 

Downstream Products

• 155730-45-3 (2R,4S,5R)-2-(1,1,1,3,3,3-Hexamethyl-disilazan-2-yl)-3,4-dimethyl-5-phenyl-[1,3,2]oxazaphospholidine 2-sulfide 

Relevant academic research and scientific papers

Stereoselective Phosphonylation of Aldehydes via Chiral Phosphordiamidites. A Potentially Versatile Asymmetric Route to Organophosphorus Biomolecules

The novel, chiral phosphordiamidite, PN(SiMe3)2 containing deprotonated ephidrine has been shown to phosphonylate aldehydes readily to afford α-functionalised phosphonate esters with diastereoselectivities up to ca. 96percent.

N,3E>-Bifunctional Phosphorodiamidites and the Diastereoselective Phosphonylation of Aldehydes. Controlling, Elucidating and Rationalising the Stereochemical Course of the Asymmetric Abramov Reaction

The novel, chiral phosphorodiamidite PN(SiMe3)2 2 has been prepared cleanly in both high chemical (83percent) and epimeric (>98percent) yields from the reaction of LiN(SiMe3)2 with PCl 1.The configuration at p