155791-24-5Relevant academic research and scientific papers
Synthesis and carbonic anhydrase inhibitory activity of 4-substituted 2- thiophenesulfonamides
Holmes,Lee,Wijono,Weinkam,Wheeler,Garst
, p. 1646 - 1651 (2007/10/02)
A series of 4-substituted 2-thiophenesulfonamides was prepared from 3- thiophenecarboxaldehyde using metalation chemistry developed for 3- furaldehyde. Several of these compounds inhibit carbonic anhydrase II in vitro at concentrations of less than 10 nM.
