15584-08-4

Basic information

• Product Name: 3-(4-chlorophenyl)-5,7-dihydroxy-4H-chromen-4-one
• Synonyms: 3-(4-chlorophenyl)-5,7-dihydroxy-4H-chromen-4-one
• CAS NO: 15584-08-4
• Molecular Formula: C₁₅H₉ClO₄
• Molecular Weight: 288.68256
• Mol File: 15584-08-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 511.3±50.0 °C(Predicted)
• Appearance: /
• Density: 1.534±0.06 g/cm3(Predicted)
• PKA: 6.34±0.20(Predicted)
• CAS DataBase Reference: 3-(4-chlorophenyl)-5,7-dihydroxy-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-chlorophenyl)-5,7-dihydroxy-4H-chromen-4-one(15584-08-4)
• EPA Substance Registry System: 3-(4-chlorophenyl)-5,7-dihydroxy-4H-chromen-4-one(15584-08-4)

Safety Data

• Hazardous Substances Data: 15584-08-4(Hazardous Substances Data)

Upstream product

• 108-73-6 3,5-dihydroxyphenol 
• 140-53-4 p-chlorobenzyl cyanide 
• 108-46-3 recorcinol 
• 15485-68-4 α-(4-chlorophenyl)-2,4,6-trihydroxyacetophenone 
• 68-12-2 N,N-dimethyl-formamide 
• 2258-42-6 formyl acetic anhydride 
• 15485-64-0 2-(4-chlorophenyl)-1-(2,4-dihydroxyphenyl)ethan-1-one 

Downstream Products

• 1445711-48-7 5-methoxy-4-oxo-3-(4-chlorophenyl)-4H-chromen-7-yl dimethylcarbamate 
• 1445711-58-9 7-hydroxy-5-methoxy-3-(4-chlorophenyl)-4H-chromen-4-one 
• 1445711-91-0 7-hydroxy-8-[(4-methylpiperazin-1-yl)methyl]-5-methoxy-3-(4-chlorophenyl)-4H-chromen-4-one 
• 1445712-00-4 7-hydroxy-5-methoxy-8-(morpholin-4-ylmethyl)-3-(4-chlorophenyl)-4H-chromen-4-one 
• 1445711-85-2 7-hydroxy-5-methoxy-8-(piperidin-1-ylmethyl)-3-(4-chlorophenyl)-4H-chromen-4-one 
• 1445711-37-4 5-hydroxy-4-oxo-3-(4-chlorophenyl)-4H-chromen-7-yl dimethylcarbamate 
• 121076-27-5 4'-chloro-5-hydroxy-7-(tetra-O-acetyl-β-D-glucopyranosyloxy)isoflavone 

Relevant articles and documents

Synthesis and aminomethylation of 7-hydroxy-5-methoxyisoflavones

A synthetic method for 7-hydroxy-5-methoxyisoflavones starting from 5,7-dihydroxyisoflavones was developed. Dimethylcarbamoylchloride was proposed for protection of the 7-hydroxy group. Aminomethylation of the synthesized 7-hydroxy-5-methoxyisoflavones by formaldehyde aminals was studied.

Synthesis and antioxidant activity of isoflavones containing hydrophilic and lipophilic substituents

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ACETOFORMIC ANHYDRIDE IN THE SYNTHESIS OF CHROMONES. 1. SYNTHESIS OF 3-HETARYLCHROMONES

It was shown that the reaction of α-(het)aryl-2,4-dihydroxy- and 2,4,6-trihydroxyacetophenones with acetoformic anhydride catalyzed by sodium formate is an effective method for the preparation of chromones containing a heteroaromatic residue at the 3-position.The yield of the chromone and the rate of the reaction increase with increase in the ?-deficiency of this residue or in the presence of a hydroxy group in the 6-position of the starting acetophenone.In the last case the method is also applicable to the preparation of the difficulty available 3-aryl-5,7-dihydroxychromones.Chromones with a nitrogen-containing residue are formed without the use of any catalyst.