155897-76-0Relevant academic research and scientific papers
Dispiroketals in Synthesis (Part 6): Highly Stereoselective Alkylation of Dispiroketal Protected Lactate and Glycolate Enolates
Downham, Robert,Kim, Kun Soo,Ley, Steven V.,Woods, Martin
, p. 769 - 772 (1994)
Protected lactic acid enolates have been alkylated with a range of electrophiles to give the substituted adducts with moderate to excellent stereoselectivity.A chiral protected glycolic acid adduct has also been doubly alkylated with high stereoselectivit
Dispiroketals in synthesis (part 10): Further reactions of dispoke protected lactate and glycolate enolates
Boons, Geert-Jan,Downham, Robert,Kim, Kun Soo,Ley, Steven V.,Woods, Martin
, p. 7157 - 7176 (2007/10/02)
α-Hydroxy acids have been reacted with bis-dihydropyrans to give dispiroketal adducts (1,8,13,16-tetraoxadispiro[5.0.5.4]-hexadecan-14-ones). The enolates derived from these compounds undergo reaction with electrophiles with generally high levels of diast
ASYMMETRIC SYNTHESIS OF (R)- AND (S)-CITRAMALATE IN HIGH ENANTIOMERIC PURITY
Frye, Stephen V.,Eliel, Ernest L.
, p. 3907 - 3910 (2007/10/02)
An asymmetric synthesis of both isomers of dimethyl 2-acetoxycitramalate in over 96percent enantiomeric excess is described.
