Dispiroketals in Synthesis (Part 6): Highly Stereoselective Alkylation of Dispiroketal Protected Lactate and Glycolate Enolates

DOI: 10.1016/S0040-4039(00)75813-8

Source and publish data:

Tetrahedron Letters p. 769 - 772 (1994)

Update date:2022-07-29

Topics:

Authors:

Downham, Robert

Kim, Kun Soo

Ley, Steven V.

Woods, Martin

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Article abstract of DOI:10.1016/S0040-4039(00)75813-8

Protected lactic acid enolates have been alkylated with a range of electrophiles to give the substituted adducts with moderate to excellent stereoselectivity.A chiral protected glycolic acid adduct has also been doubly alkylated with high stereoselectivit

Full text of DOI:10.1016/S0040-4039(00)75813-8

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