156000-82-7

Upstream product

• 110-89-4 piperidine 
• 17609-52-8 Z-D-phenylglycine 

Downstream Products

• 156000-83-8 N,N'-Bis-((R)-2-oxo-1-phenyl-2-piperidin-1-yl-ethyl)-oxalamide 
• 153837-28-6 (2,2-Me₂-propyl)-((R)-1-phenyl-2-piperidin-1-yl-ethyl)-amine 
• 142936-85-4 (R)-N-(1-phenyl-2-piperidinoethyl)trifluoroacetamide 
• 157303-87-2 (R)-N-(1-phenyl-2-piperidinoethyl)-2-acetamide 
• 157303-83-8 (R)-N-(1-phenyl-2-piperidinoethyl)-2-(2-dimethylaminoethyloxy)acetamide 
• 157303-82-7 (R)-N-(1-phenyl-2-piperidinoethyl)-2-(2-methoxyethyloxy)acetamide 
• 142950-82-1 (R)-(-)-1-(2-amino-2-phenylethyl)piperidine 
• 129157-10-4 (R)-N-isopropyl-1-phenyl-2-(1-piperidino)ethylamine 
• 148054-92-6 (R)-N-methyl-1-phenyl-2-(piperidin-1-yl) ethanamine 
• 129157-30-8 (R)-1-(2-phenylglycyl)piperidine 

Relevant academic research and scientific papers

Stereoselective reactions. XXII. Design and synthesis of chiral chelated lithium amides for enantioselective reactions

Chiral chelated lithium amides ((R))-1a-g) were designed and synthesized in optically pure forms starting from (R)-phenylglycine.

Design, synthesis, and application of chiral nonracemic lithium amide bases in enantioselective deprotonation of epoxides

The reaction of epoxides with chiral nonracemic lithium amide bases, designed and prepared from (R)-phenylglycine, has been studied in detail. A maximum of 80% ee was obtained for conversion of cyclohexene oxide to (S)-2-cyclohexen-1-ol. Enantioselective deprotonation of a variety of other epoxides was studied. A cyclopentanoid core unit for prostaglandin synthesis was synthesized in 97% ee.