129157-30-8Relevant academic research and scientific papers
A new type of L-Tertiary leucine-derived ligand: Synthesis and application in Cu(II)-catalyzed asymmetric Henry reactions
Cai, Zedong,Lan, Ting,Ma, Pengfei,Zhang, Jingfang,Yang, Qingqing,He, Wei
, (2019/08/08)
A new series of Schiff bases derived from amino acids were developed as chiral ligands for Cu(II)-catalyzed asymmetric Henry reactions. The optimum ligand 7d exhibited outstanding catalytic efficiency in the Cu(II)-catalyzed asymmetric Henry additions of four nitroalkanes to different kinds of aldehydes to produce 76 desired adducts in high yields (up to 96%) with excellent enantioselectivities, up to 99% enantiomeric excess (ee).
Stereoselective reactions. XXII. Design and synthesis of chiral chelated lithium amides for enantioselective reactions
Shirai,Aoki,Sato,Kim,Murakata,Yasukata,Koga
, p. 690 - 693 (2007/10/02)
Chiral chelated lithium amides ((R))-1a-g) were designed and synthesized in optically pure forms starting from (R)-phenylglycine.
Enantioselective conjugate addition, part V. Synthesis and testing of scalemic tetraamines as chiral cuprate ligands
Swingle, Nicole M.,Vasavi Reddy,Rossiter, Bryant E.
, p. 4455 - 4466 (2007/10/02)
Reported herein is the enantioselective conjugate addition of n-butyl to 2-cyclopentenone, 2-cyclohexenone, 2-cycloheptenone and 2-cyclooctenone using scalemic amidocuprates derived from copper(I) iodide, n-butyllithium and a homologous series of 5 scalem
ENANTIOSELECTIVE SYNTHESIS OF β-HYDROXY-α-METHYL CARBONYL COMPOUNDS BY ALDOL REACTION
Ando, Akira,Shioiri, Takayuki
, p. 4969 - 4988 (2007/10/02)
The enantioselective aldol reactions of ketone lithium enolates with aldehydes mediated chiral lithium amides were extensively investigated.The chiral amino ethers 4a-4l and diamines 16a,b were prepared from α-amino acids.The reaction conditions and the s
