156002-64-1

Basic information

• Product Name: Heterocycles
• Synonyms: Heterocycles;7-(Trifluoromethyl)quinolin-4-ol;Methyl 2-(tetrahydro-2H-pyran-4-yl)acetate;4-Bromo-2-mercaptobenzothiazole;2-Furoic thioamide;2-Pyrazinecarboxylic Hydrazide;3-Isopropyl-piperazine-2,5-dione;3-Thiophene-carboxylic Hydrazide
• CAS NO: 156002-64-1
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.2
• Product Categories: blocks;Carboxes;Heterocycles;Heterocyclic Compound;ADVANCED CHEMICALS
• Mol File: 156002-64-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 208.5±13.0 °C(Predicted)
• Appearance: /
• Density: 1.020±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Heterocycles(CAS DataBase Reference)
• NIST Chemistry Reference: Heterocycles(156002-64-1)
• EPA Substance Registry System: Heterocycles(156002-64-1)

Safety Data

• Hazardous Substances Data: 156002-64-1(Hazardous Substances Data)

Usage

General Description

Heterocycles are organic compounds that contain a ring structure with at least two different elements, including carbon and one or more non-carbon atoms such as nitrogen, oxygen, or sulfur. They are widely found in nature and are important building blocks in many biological molecules and pharmaceuticals. Heterocycles are classified into different groups based on the number of ring atoms and their arrangement, such as monocyclic, bicyclic, or tricyclic heterocycles. They exhibit diverse chemical properties and are used in various applications, including as drugs, agricultural chemicals, dyes, and fragrances. Their unique structures and reactivity make them a focus of research in organic chemistry and drug development.

Upstream product

• 67-56-1 methanol 
• 85064-61-5 2-(tetrahydro-2H-pyran-4-yl)acetic acid 
• 138302-49-5 methyl 2-(dihydro-2H-pyran-4-(3H)-ylidene)acetate 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 130312-00-4 ethyl tetrahydro-4H-pyran-4-ylideneacetate 
• 103260-44-2 ethyl tetrahydropyran-4-acetate 

Downstream Products

• 815618-35-0 (R)-4-benzyl-3-(2-(tetrahydro-2H-pyran-4-yl)acetyl)oxazolidin-2-one 
• 634908-68-2 N-(4-fluorobenzyl)-4-phenyl-3-(tetrahydro-2H-pyran-4-yl)butan-1-amine 
• 634908-64-8 N-(4-chlorobenzyl)-4-phenyl-3-(tetrahydro-2H-pyran-4-yl)butan-1-amine 

Relevant articles and documents

1H-PYRROLO[2,3-c]PYRIDIN-7(6H)-ONES AND PYRAZOLO[3,4-c]PYRIDIN-7(6H)-ONES AS INHIBITORS OF BET PROTEINS

The present invention relates to substituted pyrrolopyridinones and substituted pyrazolopyridinones which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer.

Heterocyclic compounds as P2X7 ion channel blockers

The present invention relates to a novel series of 4,5-diphenyl-2-amino-4,5-dihydro-imidazole derivatives of the formula II: 1 wherein R, R1, R2, R3, R4, R5, X and Y are as defined herein. This invention also relates to methods of making these compounds. The compounds of this invention are P2X7 ion channel blockers and are therefore useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases having an inflammatory component, including inflammatory bowel disease, rheumatoid arthritis and disease conditions associated with the central nervous system, such as stroke, Alzheimer''s disease, etc.

HYDROXAMATE SULFONAMIDES AS CD23 SHEDDING INHIBITORS

A class of piperazine and related heterocyclic derivatives, substituted at the 4-position by a substituted aryl or heteroaryl moiety, and at the 1-position by an ethylsulfonyl group which in turn is substituted at the 2-position by a hydroxamic acid moiety and also by a range of alternative substituents, being potent inhibitors of CD23 shedding, are useful in the treatment and/or prevention of allergic, inflammatory and neoplastic diseases.