1560795-87-0

Upstream product

• 171290-52-1 1-Ethynyl-3,5-dimethoxy-benzene 
• 98-09-9 benzenesulfonyl chloride 
• 875781-43-4 2-bromo-5H-pyrrolo[2,3-b]pyrazine 

Downstream Products

• 1560795-99-4 2-[2-(3,5-dimethoxyphenyl)ethyl]-5-(phenylsulfonyl)-6-(1H-pyrazol-4-yl)-5H-pyrrolo[2,3-b]pyrazine 
• 1560796-03-3 {4-[2-[2-(3,5-dimethoxyphenyl)ethyl]-5-(phenylsulfonyl)-5H-pyrrolo[2,3-b]pyrazin-6-yl]-1H-pyrazol-1-yl}acetic acid 
• 1560796-04-4 2-[2-(3,5-dimethoxyphenyl)ethyl]-6-[4-(4-methylpiperazin-1-yl)phenyl]-5-(phenylsulfonyl)-5H-pyrrolo[2,3-b]pyrazine 
• 1560796-10-2 6-bromo-2-[2-(3,5-dimethoxyphenyl)ethyl]-5H-pyrrolo[2,3-b]pyrazine 
• 1560796-16-8 4-(2-(3,5-dimethoxyphenylethyl)-5-(phenylsulfonyl)-5H-pyrrolo[2,3-b]pyrazin-6-yl)picolinonitrile 
• 1560796-17-9 4-(2-(3,5-dimethoxyphenethyl)-5H-pyrrolo[2,3-b]pyrazin-6-yl)picolinic acid 
• 1560796-25-9 6-bromo-2-(2-fluoro-3,5-dimethoxyphenethyl)-5-(phenylsulfonyl)-5H-pyrrolo[2,3-b]pyrazine 
• 1560795-89-2 6-bromo-2-[2-(3,5-dimethoxyphenyl)ethyl]-5-(phenylsulfonyl)-5H-pyrrolo[2,3-b]pyrazine 

Relevant academic research and scientific papers

Preparation of pyrrolo[2,3-b]pyrazine and pyrrolo[2,3-b]pyridine derivatives as FGFR inhibitors

The present invention relates to the preparation of compounds of formula (I) wherein R1, R2, R2a, R3, X1 to X3 have the meaning as indicated in the description and claims and to intermediat

PYRAZINE DERIVATIVES AS FGFR INHIBITORS

The present invention relates to pyrazine derivatives, and pharmaceutical compositions including the same, that are inhibitors of one or more FGFR enzymes and are useful in the treatment of FGFR-associated diseases such as cancer.