1560797-70-7

Basic information

• Product Name: (S)-4-{4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino}butyric acid D-menthyl ester L-tartrate
• Synonyms: (S)-4-{4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino}butyric acid D-menthyl ester L-tartrate
• CAS NO: 1560797-70-7
• Molecular Weight: 677.235
• Mol File: 1560797-70-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-{4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino}butyric acid D-menthyl ester L-tartrate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-{4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino}butyric acid D-menthyl ester L-tartrate(1560797-70-7)
• EPA Substance Registry System: (S)-4-{4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino}butyric acid D-menthyl ester L-tartrate(1560797-70-7)

Safety Data

• Hazardous Substances Data: 1560797-70-7(Hazardous Substances Data)

Upstream product

• 5382-16-1 4-HYDROXYPIPERIDINE 
• 1560797-83-2 D-menthyl-4-chlorobutanoate 
• 4045-22-1 N-acetyl-4-hydroxypiperidine 
• 87-69-4 L-Tartaric acid 
• 1560797-65-0 (RS)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino]butyric acid D-menthyl ester 
• 122368-54-1 4-[(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidine 

Downstream Products

• 1560797-69-4 (S)-4-[4-[(4-chlorophenyl)(2-pyridyl)methoxy]piperidino] butyric acid D-menthyl ester 
• 125602-71-3 Bepotastine 
• 125602-71-3 [14C]-Bepotastine besilate 

Relevant articles and documents

METHOD OF SYNTHESIZING BEPOTASTINE OR BENZENESULFONIC ACID SALT THEREOF AND INTERMEDIATES USED THEREIN

The present invention relates to a novel method of synthesizing bepotastine or its benzenesulfonic acid salt and novel intermediates used therein. The present invention uses L-α-hydroxy acid for chiral resolution to form an L-α-hydroxy acid salt of a compound represented by the following formula (VII-1), so as to synthesize bepotastine or its benzenesulfonic acid salt in high optical purity.