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(2R,3S)-tert-butyl 3-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate is a pyrrolidine derivative featuring a tert-butyl group and a hydroxymethyl group attached to the pyrrolidine ring. Characterized by its 2R,3S stereochemistry, (2R,3S)-tert-butyl 3-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate has a unique spatial arrangement of substituents. The presence of two hydroxyl groups on both the pyrrolidine ring and the hydroxymethyl group endows it with the capacity for intermolecular interactions and hydrogen bonding. Its complex structure and potential reactivity make it a candidate for applications in drug development, chemical synthesis, and other related fields.

156129-72-5

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156129-72-5 Usage

Uses

Used in Drug Development:
(2R,3S)-tert-butyl 3-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate is used as a building block in the synthesis of pharmaceutical compounds due to its unique stereochemistry and functional groups. Its ability to form hydrogen bonds and engage in intermolecular interactions can contribute to the design of new drugs with specific target affinities and improved pharmacokinetic properties.
Used in Chemical Synthesis:
In the chemical synthesis industry, (2R,3S)-tert-butyl 3-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate serves as an intermediate or a reactant in the production of various organic compounds. Its complex structure and reactivity make it suitable for creating novel molecules with potential applications in materials science, agrochemicals, and other specialty chemicals.
Used in Research and Development:
(2R,3S)-tert-butyl 3-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate is utilized in academic and industrial research settings to explore its chemical properties and potential applications. Its unique stereochemistry and functional groups make it an interesting subject for studies in organic chemistry, medicinal chemistry, and related fields, potentially leading to the discovery of new reactions or applications.

Check Digit Verification of cas no

The CAS Registry Mumber 156129-72-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,1,2 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 156129-72:
(8*1)+(7*5)+(6*6)+(5*1)+(4*2)+(3*9)+(2*7)+(1*2)=135
135 % 10 = 5
So 156129-72-5 is a valid CAS Registry Number.

156129-72-5Upstream product

156129-72-5Relevant academic research and scientific papers

KRAS G12C INHIBITORS

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, (2020/07/25)

The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.

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