1562-12-5

Usage

Uses

Used in Pharmaceutical Industry:
1-AMINO-4,6-DIMETHYL-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBONITRILE is used as a building block for the synthesis of various pharmaceutical compounds due to its versatile reactivity and potential biological activity. It contributes to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 1-AMINO-4,6-DIMETHYL-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBONITRILE is utilized as a key intermediate in the production of agrochemicals, such as pesticides and herbicides. Its incorporation aids in the creation of more effective and environmentally friendly products.
Used in Organic Synthesis:
1-AMINO-4,6-DIMETHYL-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBONITRILE is employed as a versatile building block in organic synthesis for the creation of a wide range of chemical compounds. Its unique structure and reactivity enable the synthesis of complex molecules with diverse applications in various industries.
Used in Research and Development:
In the field of chemical research and development, 1-AMINO-4,6-DIMETHYL-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBONITRILE is used as a valuable compound for exploring its potential biological activity and reactivity. This helps in the discovery of new chemical entities and the advancement of scientific knowledge.

InChI:InChI=1/C8H9N3O/c1-5-3-6(2)11(10)8(12)7(5)4-9/h3H,10H2,1-2H3

Upstream product

• 64-17-5 ethanol 
• 140-87-4 Cyanoacetohydrazide 
• 109-89-7 diethylamine 
• 123-54-6 acetylacetone 
• 769-28-8 3-Cyano-4,6-dimethyl-2(1H)-pyridon 
• 1218950-87-8 1,1'-{piperazine-1,4-diylbis[(Z)-methylylidenenitrilo]} bis(4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile) 

Downstream Products

• 61296-00-2 1-furfurylidenamino-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 1562-11-4 4,6-dimethyl-1-(4-nitro-benzylidenamino)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 31558-18-6 1-(2-hydroxy-benzylideneamino)-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 98334-40-8 1-amino-4,6-dimethyl-1H-pyridin-2-one 
• 98594-44-6 1-amino-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid amide 
• 109291-54-5 1-(3-Cyano-4,6-dimethyl-2-oxo-2H-pyridin-1-yl)-3-(2,6-dichloro-benzoyl)-urea 
• 108221-81-4 5,7-Dimethyl-2-((E)-styryl)-[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile 
• 31408-97-6 5,7-dimethyl-2-phenyl[1,2,4]triazolo[1,5-a]pyridine-8-carbonitrile 
• 30843-11-9 4-cyano-5,7-dimethyl-2-phenyl-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester 
• 139392-02-2 1-(2-Chloro-6-fluoro-benzoyl)-3-(3-cyano-4,6-dimethyl-2-oxo-2H-pyridin-1-yl)-urea 
• 112181-39-2 5,7-Dimethyl-2-phenyl-pyrazolo[1,5-a]pyridine-4-carbonitrile 
• 112181-41-6 3,5,7-Trimethyl-1-phenyl-1H-pyrazolo[3',4':3,4]pyrazolo[1,5-a]pyridine-4-carbonitrile 
• 183473-53-2 4,6-Dimethyl-2-oxo-1-{[1-p-tolyl-meth-(E)-ylidene]-amino}-1,2-dihydro-pyridine-3-carbonitrile 
• 183473-52-1 1-{[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-amino}-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 

Relevant academic research and scientific papers

Gas-phase pyrolysis in organic synthesis: A route for synthesis of cyanamides

(Chemical Equation Presented) Pyrolysis of 1,7-di-[(E)-1- morpholinomethylidene]- and 1,7-di-[(E)-1-piperidino-methylidene]-4,6,10,12- tetramethylamino-2,8-dioxo-1,7-diaza-3,5,9,11-cyclododecatetraene-3, 9-dicarbonitrile 6a,b afforded pyridone 10 in addition to cyanamides 11a,b. On the other hand, pyrolysis of 1-[E-(4-(E-3-cyano-4,6-dimethyl-2-oxopyridin-1(2H)- ylimino) methylpiperazin-1-yl] methylenamino-4,6-dimethyl-2-oxo-1,2- dihydropyridine-3-carbonitrile 8 gave 1-amino-4,6-dimethyl-2-oxo-1,2- dihydropyridine-3-carbonitrile 13 as well as piperazine. The mechanism of pyrolysis and the effect of stereochemistry of pyrolyzed substrates on the nature of the pyrolysates are discussed.

Comparative studies for selective deprotection of the N-arylideneamino moiety from heterocyclic amides: Kinetic and theoretical studies

The kinetics, product analysis and theoretical studies for selective deprotection of N-arylideneamino pyridone, pyrimidinone and triazinone systems were carried out. Their reactivities were compared with each other and with related compounds previously studied. This reaction represents an efficient, clean and general synthetic procedure for the protection and selective synthesis of potential biologically active pyridines, pyrimidines and triazines and their derivatives.

Pyrolysis of amino nitriles, cyanohydrazones, and cyanoacetamides. Part I. Elimination reaction of 1-arylmethyleneamino-1,2-dihydro-4, 6-dimethyl-2-oxopyridine-3-carbonitriles and substituted benzaldehyde cyanoacetylhydrazones

Pyrolysis of the Schiff bases of 1-arylmethyleneamino-1,2-dihydro-4, 6-dimethyl-2-oxopyridine-3-carbonitriles (1-5) has been studied. These compounds eliminate via a six-membered transition state to produce substituted benzonitriles and 2-hydroxy-4,6-dimethylpyridine-3-carbonitrile. These eliminations are unimolecular first-order reactions. The kinetic data gave a good correlation with σ0 values of the substituents on the aryl group with ρ = 0.83 at 520 K. Utilization of the pyrolytic reaction in synthesis of various benzonitriles is considered, and mechanistic information has been obtained by comparing the kinetic data and product analysis of the Schiff bases with their open-chain substituted benzaldehyde cyanoacetylhydrazones (6-9) analogues.

REACTIONS OF ACYLTHIOSEMICARBAZIDES WITH β-DIKETONES: NOVEL SYNTHESIS OF N-(1-PYRIDYL)THIOUREA DERIVATIVES

The reaction of 1-cyanoacetyl-4-arylthiosemicarbazides with β-diketones was studied as a new route for the synthesis of N-(1-pyridyl)thiourea derivatives.The latter compounds could also be prepared via reaction of the corresponding N-aminopyridines with a

Novel Pyrethroid Insecticides. III. Synthesis of Some N-(1-Pyridyl) Substituted Amides of Cyclopropanecarboxylic Acids

New type pyrethroid amides have been synthesized starting from the corresponding cyclopropanecarboxylic acid chlorides and N-amino-2-pyridone derivatives.