1562-16-9

Upstream product

• 59830-60-3 N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde 
• 902151-19-3 N-[1-benzyl-2-hydroxy-5-(tetrahydro-pyran-2-yloxy)-pentyl]-2-nitro-benzenesulfonamide 
• 902151-20-6 acetic acid 4-hydroxy-1-[1-(2-nitro-benzenesulfonylamino)-2-phenyl-ethyl]-butyl ester 
• 902151-21-7 acetic acid 2-benzyl-1-(2-nitro-benzenesulfonyl)-piperidin-3-yl ester 
• 902151-18-2 [1-benzyl-2-hydroxy-5-(tetrahydro-pyran-2-yloxy)-pent-3-ynyl]-carbamic acid benzyl ester 

Downstream Products

• 914924-56-4 (2-benzyl-3-hydroxy-piperidin-1-yl)-phenyl-methanone 
• 902151-22-8 2-benzyl-3-hydroxy-piperidine-1-carboxylic acid benzyl ester 
• 902151-23-9 2-benzyl-3-hydroxy-piperidine-1-carboxylic acid methyl ester 
• 914924-73-5 1-benzenesulfonyl-2-benzyl-piperidin-3-ol 
• 276872-92-5 N-(benzyloxycarbonyl)-2-phenylmethyl-3-piperidone 
• 914924-77-9 1-benzoyl-2-benzyl-piperidin-3-one 
• 914924-78-0 1-benzenesulfonyl-2-benzyl-piperidin-3-one 
• 902151-24-0 2-benzyl-3-oxo-piperidine-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Novel γ-secretase inhibitors discovered by library screening of in-house synthetic natural product intermediates

Screening of our in-house compound library comprised of intermediates of natural product synthesis projects resulted in discovering two novel γ-secretase inhibitors, which coincidently had similar moieties, that is, cyclohexenone and two aryl groups arran