276872-92-5

Upstream product

• 123-75-1 pyrrolidine 
• 61995-20-8 N-(benzyloxycarbonyl)-3-piperidone 
• 100-39-0 benzyl bromide 
• 902151-19-3 N-[1-benzyl-2-hydroxy-5-(tetrahydro-pyran-2-yloxy)-pentyl]-2-nitro-benzenesulfonamide 
• 902151-20-6 acetic acid 4-hydroxy-1-[1-(2-nitro-benzenesulfonylamino)-2-phenyl-ethyl]-butyl ester 
• 59830-60-3 N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde 
• 1562-16-9 2-Benzyl-piperidin-3-ol 
• 902151-18-2 [1-benzyl-2-hydroxy-5-(tetrahydro-pyran-2-yloxy)-pent-3-ynyl]-carbamic acid benzyl ester 
• 902151-21-7 acetic acid 2-benzyl-1-(2-nitro-benzenesulfonyl)-piperidin-3-yl ester 
• 902151-22-8 2-benzyl-3-hydroxy-piperidine-1-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Novel γ-secretase inhibitors discovered by library screening of in-house synthetic natural product intermediates

Screening of our in-house compound library comprised of intermediates of natural product synthesis projects resulted in discovering two novel γ-secretase inhibitors, which coincidently had similar moieties, that is, cyclohexenone and two aryl groups arran

Heterocycyclic piperidines as modulators of chemokine receptor activity

The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases.