156333-96-9Relevant academic research and scientific papers
An approach to α-substituted amines
Williams, Lorenzo,Booth, Susan E.,Undheim, Kjell
, p. 13697 - 13708 (1994)
A number of amines have been alkylated at the position alpha to nitrogen via free radical methodology. N-(2-iodobenzyl) and N-(2-iodobenzoyl) 'protected' amines have been used to generate radicals which rapidly undergo a 1,5-hydrogen shift to give more st
α-Alkylation of Amines via a 1,5-Hydrogen Shift
Undheim, Kjell,Williams, Lorenzo
, p. 883 - 884 (2007/10/02)
Radicals derived from N-(2-iodobenzyl) 'protected' amines undergo a 1,5-hydrogen shift to give more stable α-amino radicals, which can be subsequently trapped by electron deficient alkenes.
