An approach to α-substituted amines

Article abstract of DOI:10.1016/S0040-4020(01)85682-9

A number of amines have been alkylated at the position alpha to nitrogen via free radical methodology. N-(2-iodobenzyl) and N-(2-iodobenzoyl) 'protected' amines have been used to generate radicals which rapidly undergo a 1,5-hydrogen shift to give more st