156385-95-4

Upstream product

• 10601-19-1 5-methoxyindole-3-carboxaldehyde 
• 98-09-9 benzenesulfonyl chloride 
• 1006-94-6 5-methoxylindole 

Downstream Products

• 157891-21-9 (1-Benzenesulfonyl-5-methoxy-1H-indol-3-yl)-(1-trityl-1H-imidazol-2-yl)-methanol 
• 937803-73-1 C₃₄H₂₈N₂O₈S₂ 
• 1448696-34-1 C₂₂H₂₃NO₅S 
• 1448345-07-0 C₁₇H₁₆N₂O₆S 
• 1448344-58-8 methyl 4-((((5-methoxy-1-(phenylsulfonyl)-1H-indol-3-yl)methoxy)carbonylaminooxy)carbonyl)benzoate 
• 1448344-76-0 (2R,3S)-5-methoxy-2'-oxo-1-(phenylsulfonyl)spiro[indoline-3,4'-oxazolidine]-2-yl methyl terephthalate 
• 701204-19-5 (5-methoxy-1-(phenylsulfonyl)-1H-indol-3-yl)methanol 
• 1312447-85-0 3-methoxy-6-methyl-9-tosyl-9H-carbazole 
• 157891-22-0 (5-Methoxy-1H-indol-3-yl)-(1-trityl-1H-imidazol-2-yl)-methanol 
• 157891-23-1 5-Methoxy-3-(1-trityl-1H-imidazol-2-ylmethyl)-1H-indole 
• 869985-65-9 tert-butyl (2-iodobenzyl){[5-methoxy-1-(phenylsulfonyl)-1H-indol-3-yl]carbonyl}carbamate 
• 869985-79-5 9-methoxy-12-(phenylsulfonyl)-7-oxo-5,6,7,12-tetrahydroindolo[3,2-d][2]benzazepine-6-carboxylic acid tert-butyl ester 
• 923604-13-1 N-(2-iodobenzyl)-5-methoxy-1-(phenylsulfonyl)-1H-indole-3-carboxamide 
• 937803-64-0 C₃₄H₂₆N₂O₆S₃ 

Relevant academic research and scientific papers

Iron(II)-catalyzed asymmetric intramolecular aminohydroxylation of indoles

An enantioselective intramolecular indole aminohydroxylation reaction is catalyzed by iron(II)-chiral bisoxazoline (BOX) complexes (ee up to 99%, dr > 20:1). This discovery enables expedient asymmetric synthesis of a series of biologically active 3-amino

Synthesis and antitumor properties of 2,5-bis(3′-indolyl)thiophenes: Analogues of marine alkaloid nortopsentin

A series of 11 bis-indolylthiophenes of type 8-10 were obtained by cyclization of diketones 4 and 7 using Lawesson's reagent. Derivatives 8c, 9c, 9d, and 10c were selected to be evaluated in the full panel of about 60 human tumor cell lines derived from nine human cancer cell types and showed antiproliferative activity generally in the micromolar range. The most sensitive cell lines were: CCRF-CEM, MOLT-4, HL60 (TB), and RPMI-8226 of the leukemia subpanel, HT29 and HCC-2998 cell lines of the colon sub-panel, NCI-H522 of the non-small cell lung cancer sub-panel, LOX IMVI of the melanoma sub-panel, and UO-31 of the renal cancer sub-panel.

Fused [d]pyridazin-7-ones

The present invention is directed to fused [d]pyridazin-7-ones. The invention is also directed to methods for making and using the fused [d]pyridazin-7-ones. In particular, the compounds of the present invention may be effective in the treatment of diseases or disease states related to the activity of VEGFR2, MLK1 and CDK5 enzymes, including, for example, angiogenic disorders and neurodegenerative diseases.

N-ARYLSULFONYL-3-SUBSTITUTED INDOLES HAVING SEROTONIN RECEPTOR AFFINITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM

The present invention relates to novel N-arylsulfonyl-3-substituted indole compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their geometric forms, their N-oxides, their polymorphs, their pharmaceutically acceptable

A SHORT SYNTHESIS OF A CONFORMATIONALLY RESTRICTED ANALOG OF THE NEUROTRANSMITTER SEROTONIN WITH REDUCED BASICITY

The synthesis of a less basic, conformationally restricted analog of serotonin is described .The crucial carbon-carbon bond formation step in this synthesis involves the attack of a 2-lithioimidazole anion on an