156415-89-3

Upstream product

• 96142-63-1 (+)-(2S,3S)-8-chloro-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5H-1,5-benzothiazepin-4-one 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 1027373-55-2 [(2S,3S)-3-Acetoxy-2-(4-benzyloxy-phenyl)-8-chloro-4-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazepin-5-yl]-acetic acid 
• 156415-90-6 methyl (+)-(2S,3S)-2-(4-benzyloxyphenyl)-8-chloro-3-hydroxy-2,3,4,5-tetrahydro-4-oxo-1,5-benzothioazepin-5-acetate 
• 156415-91-7 (+)-(2S,3S)-2-(4-benzyloxyphenyl)-8-chloro-2,3,4,5-tetrahydro-3-hydroxy-4-oxo-1,5-benzothioazepin-5-acetic acid 
• 148039-96-7 (+)-(2S,3S)-8-chloro-2,3,4,5-tetrahydro-3-hydroxy-2-(4-methoxyphenyl)-4-oxo-1,5-benzothioazepin-5-acetic acid 
• 148039-98-9 (+)-(2S,3S)-8-chloro-2,3,4,5-tetrahydro-3-hydroxy-2-(4-hydroxyphenyl)-4-oxo-1,5-benzothioazepin-5-acetic acid 

Relevant academic research and scientific papers

Synthesis of the metabolites of clentiazem

The metabolites of clentiazem in the urine or bile of rats and dogs were investigated. Fifteen basic, 6 acidic, 2 neutral and 4 conjugated metabolites were isolated. In the present paper, fourteen reference compounds as shown in Charts 1, 2 and 3 were syn