156599-71-2

Basic information

• Product Name: (2R,6S,7R,9R,14S)-14-tert-Butyl-2,9-diphenyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane
• Synonyms: (2R,6S,7R,9R,14S)-14-tert-Butyl-2,9-diphenyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane
• CAS NO: 156599-71-2
• Molecular Weight: 436.591
• Mol File: 156599-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,6S,7R,9R,14S)-14-tert-Butyl-2,9-diphenyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,6S,7R,9R,14S)-14-tert-Butyl-2,9-diphenyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane(156599-71-2)
• EPA Substance Registry System: (2R,6S,7R,9R,14S)-14-tert-Butyl-2,9-diphenyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane(156599-71-2)

Safety Data

• Hazardous Substances Data: 156599-71-2(Hazardous Substances Data)

Upstream product

• 6920-22-5 Hexane-1,2-diol 
• 156599-77-8 (2R,6S,7R,9R,14S)-14-Benzyloxymethyl-2,9-diphenyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane 
• 59562-82-2 3,3-dimetylbutan-1,2-diol 
• 154859-08-2 <2R,2'R> 2,2-diphenyl-3,3',4,4'-tetrahydro-6,6'-bi-2H-pyran 

Downstream Products

• 156599-77-8 (2R,6S,7R,9R,14S)-14-Benzyloxymethyl-2,9-diphenyl-1,8,13,16-tetraoxa-dispiro[5.0.5.4]hexadecane 

Relevant articles and documents

Dispiroketals in synthesis (part 9): Resolution of 1,2-diols using a C2-symmetric diphenyltetrahydrobipyran

A series of 1,2-diols were resolved by the enantioselective formation of the thermodynamically most stable dispiroketal using (2R,2'R) and (2S,2'S) 2,2'-diphenyl-3,3',4,4'-tetrahydro-6,6'-bi-2H-pyran 2 and 3. Deprotection was achieved using a metal ammonia reduction to liberate the resolved diols.