156682-52-9

Basic information

• Product Name: 1,4-DIBROMO-2,3-DIFLUOROBENZENE
• Synonyms: 1,4-Dibromo-2,3-difluorobenzene 97%;Benzene,1,4-dibroMo-2,3-difluoro-
• CAS NO: 156682-52-9
• Molecular Formula: C₆H₂Br₂F₂
• Molecular Weight: 271.9
• EINECS: 1592732-453-0
• Mol File: 156682-52-9.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 212℃
• Flash Point: 82℃
• Appearance: /
• Density: 2.087
• Vapor Pressure: 0.259mmHg at 25°C
• Refractive Index: 1.5620-1.5660
• Storage Temp.: 0-10°C
• CAS DataBase Reference: 1,4-DIBROMO-2,3-DIFLUOROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-DIBROMO-2,3-DIFLUOROBENZENE(156682-52-9)
• EPA Substance Registry System: 1,4-DIBROMO-2,3-DIFLUOROBENZENE(156682-52-9)

Safety Data

• Hazardous Substances Data: 156682-52-9(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 156682-52-9 differently. You can refer to the following data:
1. 1,4-Dibromo-2,3-difluorobenzene is a halogenated benzene used in the preparation of various biologically active compounds such as non-nucleoside reverse transcriptase inhibitors. 1,4-Dibromo-2,3-diflu orobenzene is also used in the synthesis of conjugated polymers for organic photovoltaics.
2. 1,4-Dibromo-2,3-difluorobenzene is a halogenated benzene used in the preparation of various biologically active compounds such as non-nucleoside reverse transcriptase inhibitors. 1,4-Dibromo-2,3-difluorobenzene is also used in the synthesis of conjugated polymers for organic photovoltaics.

InChI:InChI=1/C6H2Br2F2/c7-3-1-2-4(8)6(10)5(3)9/h1-2H

Upstream product

• 75-61-6 dibromodifluoromethane 
• 38573-88-5 1-bromo-2,3-difluorobenzene 
• 867366-94-7 (2,3-difluoro-1,4-phenylene)bis(trimethylsilane) 
• 367-11-3 ortho-difluorobenzene 

Downstream Products

• 1007571-62-1 3-chloro-5-(3,6-dibromo-2-fluoro-phenoxy)-benzonitrile 
• 1309366-56-0 4,4'-(2,3-difluoro-1,4-phenylene)dipyridine 
• 1456901-31-7 6,7-difluoro-2,3-bis(3-(octyloxy)phenyl)-5,8-di(thiophen-2-yl)quinoxaline 
• 1416056-61-5 5,8-bis(5-bromothiophen-2-yl)-6,7-difluoro-2,3-bis(3-(octyloxy)phenyl)quinoxaline 
• 1415801-13-6 5,8-dibromo-6,7-difuoro-2,3-bis(3-(octyloxy)phenyl)quinoxaline 

Relevant articles and documents

NOVEL ANTIBIOTICS AND METHODS OF USING SAME

The present invention includes novel 3,6-diazabicyclo[3.1.1]heptane antibiotic compounds and any salts or solvates thereof. The present invention further includes methods of preparing such compounds, and methods of treating bacterial infection in a subjec

Molecular-level architectural design using benzothiadiazole-based polymers for photovoltaic applications

A series of low band gap, planar conjugated polymers, P1 (PFDTBT), P2 (PFDTDFBT) and P3 (PFDTTBT), based on fluorene and benzothiadiazole, was synthesized. The effect of fluorine substitution and fused aromatic spacers on the optoelectronic and photovoltaic performance was studied. The polymer, derived from dithienylated benzothiodiazole and fluorene, P1, exhibited a highest occupied molecular orbital (HOMO) energy level at -5.48 eV. Density functional theory (DFT) studies as well as experimental measurements suggested that upon substitution of the acceptor with fluorine, both the HOMO and lowest unoccupied molecular orbital (LUMO) energy levels of the resulting polymer, P2, were lowered, leading to a higher open circuit voltage and short circuit current with an overall improvement of more than 110% for the photovoltaic devices. Moreover, a decrease in the torsion angle between the units was also observed for the fluorinated polymer P2 due to the enhanced electrostatic interaction between the fluorine substituents and sulfur atoms, leading to a high hole mobility. The use of a fused π-bridge in polymer P3 for the enhancement of the planarity as compared to the P1 backbone was also studied. This enhanced planarity led to the highest observed mobility among the reported three polymers as well as to an improvement in the device efficiency by more than 40% for P3.

Quinoxaline-based polymer dots with ultrabright red to near-infrared fluorescence for in vivo biological imaging

This article describes the design and synthesis of quinoxaline-based semiconducting polymer dots (Pdots) that exhibit near-infrared fluorescence, ultrahigh brightness, large Stokes shifts, and excellent cellular targeting capability. We also introduced fluorine atoms and long alkyl chains into polymer backbones and systematically investigated their effect on the fluorescence quantum yields of Pdots. These new series of quinoxaline-based Pdots have a fluorescence quantum yield as high as 47% with a Stokes shift larger than 150 nm. Single-particle analysis reveals that the average per-particle brightness of the Pdots is at least 6 times higher than that of the commercially available quantum dots. We further demonstrated the use of this new class of quinoxaline-based Pdots for effective and specific cellular and subcellular labeling without any noticeable nonspecific binding. Moreover, the cytotoxicity of Pdots were evaluated on HeLa cells and zebrafish embryos to demonstrate their great biocompatibility. By taking advantage of their extreme brightness and minimal cytotoxicity, we performed, for the first time, in vivo microangiography imaging on living zebrafish embryos using Pdots. These quinoxaline-based NIR-fluorescent Pdots are anticipated to find broad use in a variety of in vitro and in vivo biological research.